Chlorpromazine and glucose metabolism

A. Jori, D. Bernardi, S. Garattini

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Chlorpromazine in low doses (1.25 mg kg) reduces the tolerance to glucose load for more than 24 hr. The effect is not related to changes in body temperature and is present in both adrenalectomized and adrenal demedullated rats. Part of this effect of chlorpromazine is related to changes in permeability as shown by the decreased disappearance from blood stream of arabinose, a sugar which is not phosphorilated, after arabinose load.

Original languageEnglish
Pages (from-to)553-558
Number of pages6
JournalNeuropharmacology
Volume3
Issue number6
Publication statusPublished - Dec 1964

Fingerprint

Arabinose
Chlorpromazine
Body Temperature Changes
Glucose
Permeability

ASJC Scopus subject areas

  • Medicine(all)
  • Cellular and Molecular Neuroscience
  • Drug Discovery
  • Pharmacology

Cite this

Jori, A., Bernardi, D., & Garattini, S. (1964). Chlorpromazine and glucose metabolism. Neuropharmacology, 3(6), 553-558.

Chlorpromazine and glucose metabolism. / Jori, A.; Bernardi, D.; Garattini, S.

In: Neuropharmacology, Vol. 3, No. 6, 12.1964, p. 553-558.

Research output: Contribution to journalArticle

Jori, A, Bernardi, D & Garattini, S 1964, 'Chlorpromazine and glucose metabolism', Neuropharmacology, vol. 3, no. 6, pp. 553-558.
Jori A, Bernardi D, Garattini S. Chlorpromazine and glucose metabolism. Neuropharmacology. 1964 Dec;3(6):553-558.
Jori, A. ; Bernardi, D. ; Garattini, S. / Chlorpromazine and glucose metabolism. In: Neuropharmacology. 1964 ; Vol. 3, No. 6. pp. 553-558.
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