Abstract
In 498 subjects (205 normolipidemics and 293 hyperlipidemics) of both sexes, the cholesterol content of high density lipoprotein (HDL) subfractions has been determined. The serum concentration of total HDL-cholesterol appears to be more strictly related to the cholesterol content of HDL2 than to that of HDL3. This latter one, however, gives a contribution to the variability of HDL-cholesterol so that the value of HDL-cholesterol cannot be assumed as a reliable estimate of the serum level of the more anti-atherogenic HDL2 subfraction. The cholesterol content of HDL and its subfractions is higher in women than in men and decreases with increasing serum VLDL-cholesterol level and body weight. Both HDL2- and HDL3-cholesterol appear to largely depend from the metabolism of triglyceride-rich lipoproteins in accordance with the data of experimental studies.
Original language | English |
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Pages (from-to) | 165-172 |
Number of pages | 8 |
Journal | La Ricerca in Clinica e in Laboratorio |
Volume | 19 |
Issue number | 1 |
DOIs | |
Publication status | Published - Dec 1989 |
Keywords
- HDL-cholesterol
- HDL-cholesterol
- HDL-cholesterol
- Obesity
- Serum lipoproteins
ASJC Scopus subject areas
- Clinical Biochemistry