Abstract
In 498 subjects (205 normolipidemics and 293 hyperlipidemics) of both sexes, the cholesterol content of high density lipoprotein (HDL) subfractions has been determined. The serum concentration of total HDL-cholesterol appears to be more strictly related to the cholesterol content of HDL2 than to that of HDL3. This latter one, however, gives a contribution to the variability of HDL-cholesterol so that the value of HDL-cholesterol cannot be assumed as a reliable estimate of the serum level of the more anti-atherogenic HDL2 subfraction. The cholesterol content of HDL and its subfractions is higher in women than in men and decreases with increasing serum VLDL-cholesterol level and body weight. Both HDL2- and HDL3-cholesterol appear to largely depend from the metabolism of triglyceride-rich lipoproteins in accordance with the data of experimental studies.
| Original language | English |
|---|---|
| Pages (from-to) | 165-172 |
| Number of pages | 8 |
| Journal | La Ricerca in Clinica e in Laboratorio |
| Volume | 19 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Dec 1989 |
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Keywords
- HDL-cholesterol
- HDL-cholesterol
- HDL-cholesterol
- Obesity
- Serum lipoproteins
ASJC Scopus subject areas
- Clinical Biochemistry
Cite this
Cholesterol distribution between HDL subfractions. A study of 498 subjects. / Sommariva, Domenico; Branchi, Adriana; Bonfiglioli, Daniela; Tirrito, Maria; Cabrini, Enrico; Pini, Claudio; Scandiani, Luciana; Rovellini, Angelo; Fasoli, Angelo.
In: La Ricerca in Clinica e in Laboratorio, Vol. 19, No. 1, 12.1989, p. 165-172.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cholesterol distribution between HDL subfractions. A study of 498 subjects
AU - Sommariva, Domenico
AU - Branchi, Adriana
AU - Bonfiglioli, Daniela
AU - Tirrito, Maria
AU - Cabrini, Enrico
AU - Pini, Claudio
AU - Scandiani, Luciana
AU - Rovellini, Angelo
AU - Fasoli, Angelo
PY - 1989/12
Y1 - 1989/12
N2 - In 498 subjects (205 normolipidemics and 293 hyperlipidemics) of both sexes, the cholesterol content of high density lipoprotein (HDL) subfractions has been determined. The serum concentration of total HDL-cholesterol appears to be more strictly related to the cholesterol content of HDL2 than to that of HDL3. This latter one, however, gives a contribution to the variability of HDL-cholesterol so that the value of HDL-cholesterol cannot be assumed as a reliable estimate of the serum level of the more anti-atherogenic HDL2 subfraction. The cholesterol content of HDL and its subfractions is higher in women than in men and decreases with increasing serum VLDL-cholesterol level and body weight. Both HDL2- and HDL3-cholesterol appear to largely depend from the metabolism of triglyceride-rich lipoproteins in accordance with the data of experimental studies.
AB - In 498 subjects (205 normolipidemics and 293 hyperlipidemics) of both sexes, the cholesterol content of high density lipoprotein (HDL) subfractions has been determined. The serum concentration of total HDL-cholesterol appears to be more strictly related to the cholesterol content of HDL2 than to that of HDL3. This latter one, however, gives a contribution to the variability of HDL-cholesterol so that the value of HDL-cholesterol cannot be assumed as a reliable estimate of the serum level of the more anti-atherogenic HDL2 subfraction. The cholesterol content of HDL and its subfractions is higher in women than in men and decreases with increasing serum VLDL-cholesterol level and body weight. Both HDL2- and HDL3-cholesterol appear to largely depend from the metabolism of triglyceride-rich lipoproteins in accordance with the data of experimental studies.
KW - HDL-cholesterol
KW - HDL-cholesterol
KW - HDL-cholesterol
KW - Obesity
KW - Serum lipoproteins
UR - http://www.scopus.com/inward/record.url?scp=51849180741&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=51849180741&partnerID=8YFLogxK
U2 - 10.1007/BF02871805
DO - 10.1007/BF02871805
M3 - Article
AN - SCOPUS:51849180741
VL - 19
SP - 165
EP - 172
JO - Ricerca in Clinica e in Laboratorio
JF - Ricerca in Clinica e in Laboratorio
SN - 0940-5437
IS - 1
ER -