Cholesterol distribution between HDL subfractions. A study of 498 subjects

Domenico Sommariva, Adriana Branchi, Daniela Bonfiglioli, Maria Tirrito, Enrico Cabrini, Claudio Pini, Luciana Scandiani, Angelo Rovellini, Angelo Fasoli

Research output: Contribution to journalArticle

Abstract

In 498 subjects (205 normolipidemics and 293 hyperlipidemics) of both sexes, the cholesterol content of high density lipoprotein (HDL) subfractions has been determined. The serum concentration of total HDL-cholesterol appears to be more strictly related to the cholesterol content of HDL2 than to that of HDL3. This latter one, however, gives a contribution to the variability of HDL-cholesterol so that the value of HDL-cholesterol cannot be assumed as a reliable estimate of the serum level of the more anti-atherogenic HDL2 subfraction. The cholesterol content of HDL and its subfractions is higher in women than in men and decreases with increasing serum VLDL-cholesterol level and body weight. Both HDL2- and HDL3-cholesterol appear to largely depend from the metabolism of triglyceride-rich lipoproteins in accordance with the data of experimental studies.

Original languageEnglish
Pages (from-to)165-172
Number of pages8
JournalLa Ricerca in Clinica e in Laboratorio
Volume19
Issue number1
DOIs
Publication statusPublished - Dec 1989

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HDL Lipoproteins
HDL Cholesterol
Cholesterol
Serum
VLDL Cholesterol
Metabolism
Lipoproteins
Triglycerides
Body Weight

Keywords

  • HDL-cholesterol
  • HDL-cholesterol
  • HDL-cholesterol
  • Obesity
  • Serum lipoproteins

ASJC Scopus subject areas

  • Clinical Biochemistry

Cite this

Sommariva, D., Branchi, A., Bonfiglioli, D., Tirrito, M., Cabrini, E., Pini, C., ... Fasoli, A. (1989). Cholesterol distribution between HDL subfractions. A study of 498 subjects. La Ricerca in Clinica e in Laboratorio, 19(1), 165-172. https://doi.org/10.1007/BF02871805

Cholesterol distribution between HDL subfractions. A study of 498 subjects. / Sommariva, Domenico; Branchi, Adriana; Bonfiglioli, Daniela; Tirrito, Maria; Cabrini, Enrico; Pini, Claudio; Scandiani, Luciana; Rovellini, Angelo; Fasoli, Angelo.

In: La Ricerca in Clinica e in Laboratorio, Vol. 19, No. 1, 12.1989, p. 165-172.

Research output: Contribution to journalArticle

Sommariva, D, Branchi, A, Bonfiglioli, D, Tirrito, M, Cabrini, E, Pini, C, Scandiani, L, Rovellini, A & Fasoli, A 1989, 'Cholesterol distribution between HDL subfractions. A study of 498 subjects', La Ricerca in Clinica e in Laboratorio, vol. 19, no. 1, pp. 165-172. https://doi.org/10.1007/BF02871805
Sommariva, Domenico ; Branchi, Adriana ; Bonfiglioli, Daniela ; Tirrito, Maria ; Cabrini, Enrico ; Pini, Claudio ; Scandiani, Luciana ; Rovellini, Angelo ; Fasoli, Angelo. / Cholesterol distribution between HDL subfractions. A study of 498 subjects. In: La Ricerca in Clinica e in Laboratorio. 1989 ; Vol. 19, No. 1. pp. 165-172.
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