Choosing Wisely: The Top-5 Recommendations from the Italian Panel of the National Guidelines for the Management of Acute Pharyngitis in Children

E. Chiappini, B. Bortone, G. Di Mauro, S. Esposito, L. Galli, M. Landi, A. Novelli, P. Marchisio, G.L. Marseglia, N. Principi, M. de Martino

Research output: Contribution to journalArticle


Purpose With the aim to reduce waste in the health care system and avoid risks associated with unnecessary treatment, the Italian Panel of the National Guidelines for the Management of Acute Pharyngitis in Children joined the Choosing Wisely initiative. Methods An ad hoc Choosing Wisely task force was selected to develop a candidate list of items for the top-5 list on pharyngitis medicine. Through a process of literature review and consensus, the final list of 5 items was chosen. Drafted recommendations were formulated and then reviewed by the task force members until a final consensus was reached. Findings The 5 recommendations approved are: blood exams should not be performed; antibiotics should not be administrated unless microbiologic confirmation of streptococcal infection has been carried out; if a throat culture is performed, susceptibility tests on isolates should not be executed; antibiotic course should not be shortened; because penicillin V is not available in Italy, amoxicillin (50 mg/kg/d in 2–3 doses orally) for 10 days is the first choice treatment; and steroids should not be administered for the risk of masking possible underlying severe condition. Implications This top-5 list can be a novel tool to spread the key messages of guidelines and to avoid unnecessary diagnostic procedures, and to promote a rational use of antibiotics in children. © 2017 Elsevier HS Journals, Inc.
Original languageEnglish
Pages (from-to)646-649
Number of pages4
JournalClinical Therapeutics
Issue number3
Publication statusPublished - 2017



  • amoxicillin
  • antibiotic agent
  • benzathine penicillin
  • penicillin V
  • steroid
  • antiinfective agent, antibiotic sensitivity
  • Article
  • bacterium isolate
  • blood analysis
  • child
  • health care system
  • human
  • Italy
  • medicine
  • pharyngitis
  • practice guideline
  • risk
  • risk reduction
  • streptococcal pharyngitis
  • throat culture
  • Streptococcal Infections, Anti-Bacterial Agents
  • Child
  • Humans
  • Pharyngitis
  • Streptococcal Infections

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