Choroidal caverns: A previously unreported optical coherence tomography finding in best vitelliform dystrophy

Adriano Carnevali; R Sacconi; Eleonora Corbelli; L Querques; F Bandello; G Querques

doi:10.3928/23258160-20180329-14

Choroidal caverns: A previously unreported optical coherence tomography finding in best vitelliform dystrophy

Adriano Carnevali, R Sacconi, Eleonora Corbelli, L Querques, F Bandello, G Querques

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Best vitelliform macular dystrophy (VMD) is an autosomal dominant inherited dystrophy, most frequently caused by mutations in the BEST1 gene. The authors describe “choroidal caverns,” a previously unreported optical coherence tomography finding in the choriocapillary and choroid of Best VMD. Histopathologic examination in eyes with Best VDM shows extensive deposition of lipofuscin in the retinal pigment epithelium (RPE) throughout the retina and accumulation of fibrillar material under the RPE and in the choroid. This supports the hypothesis that choroidal caverns could be a sign of the degenerative process involving the choroid in eyes with Best VMD. © 2018 Slack Incorporated. All rights reserved.

Original language	English
Pages (from-to)	284-287
Number of pages	4
Journal	Ophthalmic Surgery Lasers and Imaging Retina
Volume	49
Issue number	4
DOIs	https://doi.org/10.3928/23258160-20180329-14
Publication status	Published - 2018

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title = "Choroidal caverns: A previously unreported optical coherence tomography finding in best vitelliform dystrophy",

abstract = "Best vitelliform macular dystrophy (VMD) is an autosomal dominant inherited dystrophy, most frequently caused by mutations in the BEST1 gene. The authors describe “choroidal caverns,” a previously unreported optical coherence tomography finding in the choriocapillary and choroid of Best VMD. Histopathologic examination in eyes with Best VDM shows extensive deposition of lipofuscin in the retinal pigment epithelium (RPE) throughout the retina and accumulation of fibrillar material under the RPE and in the choroid. This supports the hypothesis that choroidal caverns could be a sign of the degenerative process involving the choroid in eyes with Best VMD. {\textcopyright} 2018 Slack Incorporated. All rights reserved.",

author = "Adriano Carnevali and R Sacconi and Eleonora Corbelli and L Querques and F Bandello and G Querques",

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T1 - Choroidal caverns: A previously unreported optical coherence tomography finding in best vitelliform dystrophy

AU - Carnevali, Adriano

AU - Sacconi, R

AU - Corbelli, Eleonora

AU - Querques, L

AU - Bandello, F

AU - Querques, G

PY - 2018

Y1 - 2018

N2 - Best vitelliform macular dystrophy (VMD) is an autosomal dominant inherited dystrophy, most frequently caused by mutations in the BEST1 gene. The authors describe “choroidal caverns,” a previously unreported optical coherence tomography finding in the choriocapillary and choroid of Best VMD. Histopathologic examination in eyes with Best VDM shows extensive deposition of lipofuscin in the retinal pigment epithelium (RPE) throughout the retina and accumulation of fibrillar material under the RPE and in the choroid. This supports the hypothesis that choroidal caverns could be a sign of the degenerative process involving the choroid in eyes with Best VMD. © 2018 Slack Incorporated. All rights reserved.

AB - Best vitelliform macular dystrophy (VMD) is an autosomal dominant inherited dystrophy, most frequently caused by mutations in the BEST1 gene. The authors describe “choroidal caverns,” a previously unreported optical coherence tomography finding in the choriocapillary and choroid of Best VMD. Histopathologic examination in eyes with Best VDM shows extensive deposition of lipofuscin in the retinal pigment epithelium (RPE) throughout the retina and accumulation of fibrillar material under the RPE and in the choroid. This supports the hypothesis that choroidal caverns could be a sign of the degenerative process involving the choroid in eyes with Best VMD. © 2018 Slack Incorporated. All rights reserved.

U2 - 10.3928/23258160-20180329-14

DO - 10.3928/23258160-20180329-14

M3 - Article

VL - 49

SP - 284

EP - 287

JO - Ophthalmic Surgery Lasers and Imaging Retina

JF - Ophthalmic Surgery Lasers and Imaging Retina

SN - 2325-8160

IS - 4

ER -