Abstract
Purpose: To report delay in choroidal perfusion suggestive of ischemia after photodynamic therapy (PDT) with verteporfin for choroidal neovascularization (CNV). Design: Observational case series. Methods: Retrospective review of all patients who developed choroidal ischemia after PDT. Results: This vascular change was found in eight (2.1%) of 373 eyes of patients treated for CNV as a result of age-related macular degeneration (AMD) and in one (0.9%) of 114 eyes treated for pathologic myopia. A decrease of 3 lines of vision was reported to occur one week after treatment in patients with AMD. At the 12-month examination, patients did not exhibit any marked changes in visual acuity. Conclusions: Choroidal ischemia was an uncommon manifestation owing to the selectivity of verteporfin therapy and the existence of abundant anastomotic vascular connections in the choroid. The low incidence of this vascular event should not preclude counseling PDT in eyes that could benefit greatly from this therapy.
| Original language | English |
|---|---|
| Pages (from-to) | 680-683 |
| Number of pages | 4 |
| Journal | American Journal of Ophthalmology |
| Volume | 142 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Oct 2006 |
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ASJC Scopus subject areas
- Ophthalmology
Cite this
Choroidal Ischemia After Photodynamic Therapy With Verteporfin for Choroidal Neovascularization. / Isola, Vincenzo; Pece, Alfredo; Parodi, Maurizio Battaglia.
In: American Journal of Ophthalmology, Vol. 142, No. 4, 10.2006, p. 680-683.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Choroidal Ischemia After Photodynamic Therapy With Verteporfin for Choroidal Neovascularization
AU - Isola, Vincenzo
AU - Pece, Alfredo
AU - Parodi, Maurizio Battaglia
PY - 2006/10
Y1 - 2006/10
N2 - Purpose: To report delay in choroidal perfusion suggestive of ischemia after photodynamic therapy (PDT) with verteporfin for choroidal neovascularization (CNV). Design: Observational case series. Methods: Retrospective review of all patients who developed choroidal ischemia after PDT. Results: This vascular change was found in eight (2.1%) of 373 eyes of patients treated for CNV as a result of age-related macular degeneration (AMD) and in one (0.9%) of 114 eyes treated for pathologic myopia. A decrease of 3 lines of vision was reported to occur one week after treatment in patients with AMD. At the 12-month examination, patients did not exhibit any marked changes in visual acuity. Conclusions: Choroidal ischemia was an uncommon manifestation owing to the selectivity of verteporfin therapy and the existence of abundant anastomotic vascular connections in the choroid. The low incidence of this vascular event should not preclude counseling PDT in eyes that could benefit greatly from this therapy.
AB - Purpose: To report delay in choroidal perfusion suggestive of ischemia after photodynamic therapy (PDT) with verteporfin for choroidal neovascularization (CNV). Design: Observational case series. Methods: Retrospective review of all patients who developed choroidal ischemia after PDT. Results: This vascular change was found in eight (2.1%) of 373 eyes of patients treated for CNV as a result of age-related macular degeneration (AMD) and in one (0.9%) of 114 eyes treated for pathologic myopia. A decrease of 3 lines of vision was reported to occur one week after treatment in patients with AMD. At the 12-month examination, patients did not exhibit any marked changes in visual acuity. Conclusions: Choroidal ischemia was an uncommon manifestation owing to the selectivity of verteporfin therapy and the existence of abundant anastomotic vascular connections in the choroid. The low incidence of this vascular event should not preclude counseling PDT in eyes that could benefit greatly from this therapy.
UR - http://www.scopus.com/inward/record.url?scp=33748953200&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33748953200&partnerID=8YFLogxK
U2 - 10.1016/j.ajo.2006.04.028
DO - 10.1016/j.ajo.2006.04.028
M3 - Article
C2 - 17011867
AN - SCOPUS:33748953200
VL - 142
SP - 680
EP - 683
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 4
ER -