Choroidal neovascularization in a patient with crohn's disease

Giuseppe Casalino, Giuseppe Querques, Federico Corvi, Enrico Borrelli, Giacinto Triolo, Giuseppe Alvise Ramirez, Francesco Bandello

Research output: Contribution to journalArticlepeer-review


Purpose: To report a case of subfoveal choroidal neovascularization (CNV) in a patient with Crohn's disease (CD) and to discuss a possible association between these two conditions. Methods: This is an observational case report. Results: A 69-year-old male affected by CD was referred to our department because of sudden visual acuity drop in the left eye. A subfoveal CNV was diagnosed based on slit-lamp fundus biomicroscopy and fluorescein angiography. Color fundus photography, infrared autofluorescence and spectral-domain optical coherence tomography imaging of both eyes were also performed. Following six intravitreal ranibizumab injections, visual improvement was obtained with no related adverse events. Conclusion: We report a case of CNV as a possible rare extraintestinal manifestation of CD. The use of ranibizumab successfully impacted on CNV, while not affecting CD, which remained quiescent.

Original languageEnglish
Pages (from-to)249-254
Number of pages6
JournalCase Reports in Ophthalmology
Issue number2
Publication statusPublished - May 22 2014


  • Anti-VEGF
  • Choroidal neovascularization
  • Crohn's disease
  • Fluorescein angiography
  • Intravitreal ranibizumab
  • Optical coherence tomography

ASJC Scopus subject areas

  • Ophthalmology


Dive into the research topics of 'Choroidal neovascularization in a patient with crohn's disease'. Together they form a unique fingerprint.

Cite this