Choroidal neovascularization in angioid streaks and pseudoxanthoma elasticum

1 year follow-up

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Purpose. To report the efficacy of intravitreal injection of bevacizumab 7.25 mg (IVB) in the treatment of choroidal neovascularization (CNV) secondary to angioid streaks (AS). Methods. Case review of two patients with CNV secondary to AS treated with three IVB with a 1-year follow-up. Results. In both patients after 1 year fluorescein angiography and optical coherence tomography showed complete inactivity of the CNV and the ophthalmologic examination revealed stabilization of the visual acuity. Conclusions. The IBV appeared to be an effective and safe treatment for CNV secondary to AS resulting in a long-term CNV inactivation. Further long-term studies in this type of lesion are desirable.

Original languageEnglish
Pages (from-to)151-153
Number of pages3
JournalEuropean Journal of Ophthalmology
Volume19
Issue number1
Publication statusPublished - 2009

Fingerprint

Angioid Streaks
Pseudoxanthoma Elasticum
Choroidal Neovascularization
Intravitreal Injections
Fluorescein Angiography
Optical Coherence Tomography
Visual Acuity
Therapeutics

Keywords

  • Angioid streaks
  • Anti-VEGF
  • Avastin
  • Choroidal neovascularization
  • Intravitreal bevacizumab

ASJC Scopus subject areas

  • Ophthalmology

Cite this

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title = "Choroidal neovascularization in angioid streaks and pseudoxanthoma elasticum: 1 year follow-up",
abstract = "Purpose. To report the efficacy of intravitreal injection of bevacizumab 7.25 mg (IVB) in the treatment of choroidal neovascularization (CNV) secondary to angioid streaks (AS). Methods. Case review of two patients with CNV secondary to AS treated with three IVB with a 1-year follow-up. Results. In both patients after 1 year fluorescein angiography and optical coherence tomography showed complete inactivity of the CNV and the ophthalmologic examination revealed stabilization of the visual acuity. Conclusions. The IBV appeared to be an effective and safe treatment for CNV secondary to AS resulting in a long-term CNV inactivation. Further long-term studies in this type of lesion are desirable.",
keywords = "Angioid streaks, Anti-VEGF, Avastin, Choroidal neovascularization, Intravitreal bevacizumab",
author = "Lomoriello, {Domenico Schiano} and M. Parravano and A. Chiaravalloti and M. Varano",
year = "2009",
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volume = "19",
pages = "151--153",
journal = "European Journal of Ophthalmology",
issn = "1120-6721",
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TY - JOUR

T1 - Choroidal neovascularization in angioid streaks and pseudoxanthoma elasticum

T2 - 1 year follow-up

AU - Lomoriello, Domenico Schiano

AU - Parravano, M.

AU - Chiaravalloti, A.

AU - Varano, M.

PY - 2009

Y1 - 2009

N2 - Purpose. To report the efficacy of intravitreal injection of bevacizumab 7.25 mg (IVB) in the treatment of choroidal neovascularization (CNV) secondary to angioid streaks (AS). Methods. Case review of two patients with CNV secondary to AS treated with three IVB with a 1-year follow-up. Results. In both patients after 1 year fluorescein angiography and optical coherence tomography showed complete inactivity of the CNV and the ophthalmologic examination revealed stabilization of the visual acuity. Conclusions. The IBV appeared to be an effective and safe treatment for CNV secondary to AS resulting in a long-term CNV inactivation. Further long-term studies in this type of lesion are desirable.

AB - Purpose. To report the efficacy of intravitreal injection of bevacizumab 7.25 mg (IVB) in the treatment of choroidal neovascularization (CNV) secondary to angioid streaks (AS). Methods. Case review of two patients with CNV secondary to AS treated with three IVB with a 1-year follow-up. Results. In both patients after 1 year fluorescein angiography and optical coherence tomography showed complete inactivity of the CNV and the ophthalmologic examination revealed stabilization of the visual acuity. Conclusions. The IBV appeared to be an effective and safe treatment for CNV secondary to AS resulting in a long-term CNV inactivation. Further long-term studies in this type of lesion are desirable.

KW - Angioid streaks

KW - Anti-VEGF

KW - Avastin

KW - Choroidal neovascularization

KW - Intravitreal bevacizumab

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EP - 153

JO - European Journal of Ophthalmology

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