Abstract
The mitogen-activated protein kinase (MAPK) signaling cascade is one of the most important mechanisms for the cytoplasmic transduction of extracellular signals. We report the chromosomal localization of the human MEK1, MEK3, MEK4 and MEKK5 genes, involved in the MAPK cascade. Using radiation hybrid mapping, MEK1 was assigned to chromosome 15q22.1→q22.33, MEK3 to chromosome 17q11.2, MEK4 to chromosome 17p12 and MEKK5 to chromosome 6q22.33.
| Original language | English |
|---|---|
| Pages (from-to) | 301-303 |
| Number of pages | 3 |
| Journal | Cytogenetics and Cell Genetics |
| Volume | 78 |
| Issue number | 3-4 |
| Publication status | Published - 1997 |
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ASJC Scopus subject areas
- Genetics
- Cell Biology
Cite this
Chromosomal localization of four MAPK signaling cascade genes : MEK1, MEK3, MEK4 and MEKK5. / Rampoldi, L.; Zimbello, R.; Bortoluzzi, S.; Tiso, N.; Valle, G.; Lanfranchi, G.; Danieli, G. A.
In: Cytogenetics and Cell Genetics, Vol. 78, No. 3-4, 1997, p. 301-303.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Chromosomal localization of four MAPK signaling cascade genes
T2 - MEK1, MEK3, MEK4 and MEKK5
AU - Rampoldi, L.
AU - Zimbello, R.
AU - Bortoluzzi, S.
AU - Tiso, N.
AU - Valle, G.
AU - Lanfranchi, G.
AU - Danieli, G. A.
PY - 1997
Y1 - 1997
N2 - The mitogen-activated protein kinase (MAPK) signaling cascade is one of the most important mechanisms for the cytoplasmic transduction of extracellular signals. We report the chromosomal localization of the human MEK1, MEK3, MEK4 and MEKK5 genes, involved in the MAPK cascade. Using radiation hybrid mapping, MEK1 was assigned to chromosome 15q22.1→q22.33, MEK3 to chromosome 17q11.2, MEK4 to chromosome 17p12 and MEKK5 to chromosome 6q22.33.
AB - The mitogen-activated protein kinase (MAPK) signaling cascade is one of the most important mechanisms for the cytoplasmic transduction of extracellular signals. We report the chromosomal localization of the human MEK1, MEK3, MEK4 and MEKK5 genes, involved in the MAPK cascade. Using radiation hybrid mapping, MEK1 was assigned to chromosome 15q22.1→q22.33, MEK3 to chromosome 17q11.2, MEK4 to chromosome 17p12 and MEKK5 to chromosome 6q22.33.
UR - http://www.scopus.com/inward/record.url?scp=0031444846&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031444846&partnerID=8YFLogxK
M3 - Article
C2 - 9465908
AN - SCOPUS:0031444846
VL - 78
SP - 301
EP - 303
JO - Cytogenetics and Cell Genetics
JF - Cytogenetics and Cell Genetics
SN - 0301-0171
IS - 3-4
ER -