Chromosomal proteins in human B and T lymphocytes.

L. Cocco, A. Facchini, N. M. Maraldi, S. Capitani, F. A. Manzoli

Research output: Contribution to journalArticlepeer-review


Histones and non-histone chromosomal proteins were characterized in B and T human lymphocytes by means of polyacrylamide disc gel electrophoresis. It was found that while histones do not present appreciable differences in the two examined populations, non-histone chromosomal proteins exhibit distinct electrophoretic profiles. Low molecular weight proteins predominate in B lymphocytes whereas high and intermediate proteins are largely represented in T lymphocytes. The latter proteins may be related to the capability of these resting cells to proliferate under appropriate antigenic stimuli.

Original languageEnglish
Pages (from-to)319-325
Number of pages7
JournalPhysiological chemistry and physics
Issue number4
Publication statusPublished - 1976

ASJC Scopus subject areas

  • Medicine(all)


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