Abstract
Histones and non-histone chromosomal proteins were characterized in B and T human lymphocytes by means of polyacrylamide disc gel electrophoresis. It was found that while histones do not present appreciable differences in the two examined populations, non-histone chromosomal proteins exhibit distinct electrophoretic profiles. Low molecular weight proteins predominate in B lymphocytes whereas high and intermediate proteins are largely represented in T lymphocytes. The latter proteins may be related to the capability of these resting cells to proliferate under appropriate antigenic stimuli.
| Original language | English |
|---|---|
| Pages (from-to) | 319-325 |
| Number of pages | 7 |
| Journal | Physiological chemistry and physics |
| Volume | 8 |
| Issue number | 4 |
| Publication status | Published - 1976 |
ASJC Scopus subject areas
- Medicine(all)
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Cocco, L., Facchini, A., Maraldi, N. M., Capitani, S., & Manzoli, F. A. (1976). Chromosomal proteins in human B and T lymphocytes. Physiological chemistry and physics, 8(4), 319-325.