Chromosome instability and translocation t(11;18) in primary gastric marginal zone B-cell lymphoma of MALT-type

Maria Grazia Tibiletti, Katia Milani, Vittoria Martin, Emanuele Zucca, Teresio Motta, Sergio Cortelazzo, Graziella Pinotti, Luca Mazzucchelli, Giancarlo Pruneri, Giovanni Martinelli, Renzo Barbazza, Carlo Capella, Francesco Bertoni

Research output: Contribution to journalArticle

Abstract

The prognosis for patients with mucosa-associated lymphoid tissue (MALT) lymphomas is good; these tumours have usually an indolent course with overall survival rates that are greater than 80% at 5-year, but some rare cases with histological transformation in aggressive diffuse large cell lymphoma have also been diagnosed. Here, we present cytogenetic results on endoscopic bioptic material of 42 cases of primary gastric extranodal marginal zone B-cell lymphoma (EMZL) using fluorescence in situ hybridization (FISH) approach with API2, MALT1 and centromeric probes for chromosome 3 and 18, and their impact on the clinical outcome.

Original languageEnglish
Pages (from-to)184-188
Number of pages5
JournalHematological Oncology
Volume25
Issue number4
DOIs
Publication statusPublished - Dec 2007

Keywords

  • Antibiotics
  • API2
  • FISH
  • MALT
  • MALT1
  • Marginal zone
  • Stomach

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'Chromosome instability and translocation t(11;18) in primary gastric marginal zone B-cell lymphoma of MALT-type'. Together they form a unique fingerprint.

  • Cite this

    Tibiletti, M. G., Milani, K., Martin, V., Zucca, E., Motta, T., Cortelazzo, S., Pinotti, G., Mazzucchelli, L., Pruneri, G., Martinelli, G., Barbazza, R., Capella, C., & Bertoni, F. (2007). Chromosome instability and translocation t(11;18) in primary gastric marginal zone B-cell lymphoma of MALT-type. Hematological Oncology, 25(4), 184-188. https://doi.org/10.1002/hon.825