Abstract
Objectives: To evaluate the relationship between chronic cerebrospinal venous insufficiency (CCSVI) and the presence of a Chronic Venous Disorder (CVD). Method: We included 55 subjects with CCSVI aged >18 years, and 186 controls without CCSVI. Each subject was evaluated with color Doppler sonography in accordance with Zamboni’s five criteria, examined by two neurologists and interviewed with an ad-hoc designed form. The neurologists and the sonographers were mutually blinded. CVD were classified according to CEAP. Results: Mean age was 42 years (SD = 9) in cases and 43 years (10) in controls (p = ns). The odds ratios in subjects CCSVI were 0.6 (0.2-2.2) for CEAP 1, 0.9 (0.2-4.5) for CEAP 2, and 1.0 (0.6-1.9) for family history of varicose veins. The prevalence of CVD and, family history of varicose veins, was similar between cases and controls for each Zamboni criterion. Conclusions: We found no association of CCSVI with the presence of CVD or family history of varicose veins.
| Original language | English |
|---|---|
| Pages (from-to) | 736-738 |
| Number of pages | 3 |
| Journal | Phlebology |
| Volume | 30 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Jan 1 2015 |
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Keywords
- Blinding
- CCSVI
- CEAP
- Multiple sclerosis
- Veins
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Chronic cerebrospinal venous insufficiency is not associated with chronic venous disorders : A case-control study. / Leone, Maurizio A.; Raymkulova, Olga; Lochner, Piergiorgio; Bolamperti, Laura; Rivadossi, Gianandrea; Stecco, Alessandro; Zaccala, Giuseppe; Maggio, Maurizio; Liboni, William; Guido, Marilena; Coppo, Lorenzo; Daniele, Imperiale.
In: Phlebology, Vol. 30, No. 10, 01.01.2015, p. 736-738.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Chronic cerebrospinal venous insufficiency is not associated with chronic venous disorders
T2 - A case-control study
AU - Leone, Maurizio A.
AU - Raymkulova, Olga
AU - Lochner, Piergiorgio
AU - Bolamperti, Laura
AU - Rivadossi, Gianandrea
AU - Stecco, Alessandro
AU - Zaccala, Giuseppe
AU - Maggio, Maurizio
AU - Liboni, William
AU - Guido, Marilena
AU - Coppo, Lorenzo
AU - Daniele, Imperiale
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Objectives: To evaluate the relationship between chronic cerebrospinal venous insufficiency (CCSVI) and the presence of a Chronic Venous Disorder (CVD). Method: We included 55 subjects with CCSVI aged >18 years, and 186 controls without CCSVI. Each subject was evaluated with color Doppler sonography in accordance with Zamboni’s five criteria, examined by two neurologists and interviewed with an ad-hoc designed form. The neurologists and the sonographers were mutually blinded. CVD were classified according to CEAP. Results: Mean age was 42 years (SD = 9) in cases and 43 years (10) in controls (p = ns). The odds ratios in subjects CCSVI were 0.6 (0.2-2.2) for CEAP 1, 0.9 (0.2-4.5) for CEAP 2, and 1.0 (0.6-1.9) for family history of varicose veins. The prevalence of CVD and, family history of varicose veins, was similar between cases and controls for each Zamboni criterion. Conclusions: We found no association of CCSVI with the presence of CVD or family history of varicose veins.
AB - Objectives: To evaluate the relationship between chronic cerebrospinal venous insufficiency (CCSVI) and the presence of a Chronic Venous Disorder (CVD). Method: We included 55 subjects with CCSVI aged >18 years, and 186 controls without CCSVI. Each subject was evaluated with color Doppler sonography in accordance with Zamboni’s five criteria, examined by two neurologists and interviewed with an ad-hoc designed form. The neurologists and the sonographers were mutually blinded. CVD were classified according to CEAP. Results: Mean age was 42 years (SD = 9) in cases and 43 years (10) in controls (p = ns). The odds ratios in subjects CCSVI were 0.6 (0.2-2.2) for CEAP 1, 0.9 (0.2-4.5) for CEAP 2, and 1.0 (0.6-1.9) for family history of varicose veins. The prevalence of CVD and, family history of varicose veins, was similar between cases and controls for each Zamboni criterion. Conclusions: We found no association of CCSVI with the presence of CVD or family history of varicose veins.
KW - Blinding
KW - CCSVI
KW - CEAP
KW - Multiple sclerosis
KW - Veins
UR - http://www.scopus.com/inward/record.url?scp=84960331104&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84960331104&partnerID=8YFLogxK
U2 - 10.1177/0268355514544782
DO - 10.1177/0268355514544782
M3 - Article
VL - 30
SP - 736
EP - 738
JO - Phlebology
JF - Phlebology
SN - 1433-3031
IS - 10
ER -