TY - JOUR
T1 - La sindrome da stanchezza cronica
AU - Carlo-Stella, Nicoletta
AU - Lorusso, Lorenzo
AU - Candura, Stefano M.
AU - Cuccia, Mariaclara
PY - 2004/11
Y1 - 2004/11
N2 - Chronic fatigue sindrome is a relatively unknown and underdiagnosed entity in Italy where its epidemiology remains uncertain, as well as its etiology, although it causes important disability in those affected. Classification criteria by Fukuda are available to diagnose the syndrome. Its epidemiology indicates that it is probably more frequent in Northern countries and it is described in Gulf War veterans. Etiological hypotheses include infectious diseases, immunology and neurology. Among these hypotheses sickness behavior mimes certain aspects of this syndrome and is characterized by a cytokine imbalance in the central nervous system and in the periphery. There are no valid therapies available at the moment. In the laboratory of Immunogenetics, we are constituting a biological bank of the syndrome to study the immunogenetic aspects of the disease in the hope of delucidating some of the obscure areas of its etiopathogenesis.
AB - Chronic fatigue sindrome is a relatively unknown and underdiagnosed entity in Italy where its epidemiology remains uncertain, as well as its etiology, although it causes important disability in those affected. Classification criteria by Fukuda are available to diagnose the syndrome. Its epidemiology indicates that it is probably more frequent in Northern countries and it is described in Gulf War veterans. Etiological hypotheses include infectious diseases, immunology and neurology. Among these hypotheses sickness behavior mimes certain aspects of this syndrome and is characterized by a cytokine imbalance in the central nervous system and in the periphery. There are no valid therapies available at the moment. In the laboratory of Immunogenetics, we are constituting a biological bank of the syndrome to study the immunogenetic aspects of the disease in the hope of delucidating some of the obscure areas of its etiopathogenesis.
KW - Chronic fatigue syndrome
KW - Cytokines
KW - Immunogenetics sickness behavior
UR - http://www.scopus.com/inward/record.url?scp=19644400779&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=19644400779&partnerID=8YFLogxK
M3 - Articolo
C2 - 15598093
AN - SCOPUS:19644400779
VL - 95
JO - Recenti Progressi in Medicina
JF - Recenti Progressi in Medicina
SN - 0034-1193
IS - 11
ER -