Chronic headaches: Pharmacological and non-pharmacological treatment

Licia Grazzi, S. Usai, G. Bussone

Research output: Contribution to journalArticlepeer-review


Chronic headaches have increasingly become a focus within the field of head pain. Most patients with frequent headache eventually overuse their medications, and when it happens, the diagnosis of medication-overuse headache is clinically important, because patients rarely respond to preventive medications whilst overusing acute medications. Properly treating medication overuse and preventing relapse require recognition of the different factors that contribute to its development and perpetuation, including some behaviours and psychological elements that are important in sustaining the overuse of medication. The different therapeutical approaches, pharmacological and nonpharmacological, initial outcomes and long-term durability of treatment are discussed.

Original languageEnglish
JournalNeurological Sciences
Issue numberSUPPL. 2
Publication statusPublished - May 2007


  • Chronic headache
  • Medication overuse headache
  • Non-pharmacological approaches
  • Pharmacological treatment

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


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