Chronic heat-induced skin lesions (Erythema ab Igne): Ultrastructural studies

V. Cavallari, R. Cicciarello, V. Torre, M. Ester Gagliardi, F. Albiero, R. Palazzo, M. Siragusa, C. Schipis

Research output: Contribution to journalArticle

Abstract

Erythema ab igne (El) is an uncommon skin lesion caused by mild and repeated exposure to infrared sources. The aim of this study was to investigate the ultrastructural alterations in this condition. The ultrastructural study was carried out on 5-outpatients who presented typical El of their exposed sites. Skin punch biopsies were processed for standard electron microscopy. The epidermis was hyperpigmented, with focal regressive changes of basal keratinocytes. An apparent functional activation of melanocytes with numerical increase of dendritic processes was also observed. The dermis showed abundant melanophages and occasional elastic fiber alterations similar to actinic elastosis. No alterations consistent with preneoplastic skin conditions were observed. The ultrastructural findings associated with El seem to be nonspecific and consistent with moderate regressive changes of keratinocytes as well as a consensual melanocytic activation and elastic fiber modifications. Similar alterations can be observed in chronic actinic skin damage. This condition is presumably more benign than the ultraviolet exposure. The association of El and premalignant skin lesions, though occasionally described, seems relatively infrequent.

Original languageEnglish
Pages (from-to)93-97
Number of pages5
JournalUltrastructural Pathology
Volume25
Issue number2
Publication statusPublished - 2001

Fingerprint

Erythema
lesions
Skin
Hot Temperature
heat
Elastic Tissue
Keratinocytes
Chemical activation
Precancerous Conditions
activation
epidermis
punches
fibers
Fibers
Biopsy
Melanocytes
Dermis
Epidermis
Electron microscopy
electron microscopy

Keywords

  • Erythema ab igne
  • Mental retardation
  • Ultrastructure

ASJC Scopus subject areas

  • Structural Biology
  • Pathology and Forensic Medicine
  • Instrumentation

Cite this

Cavallari, V., Cicciarello, R., Torre, V., Ester Gagliardi, M., Albiero, F., Palazzo, R., ... Schipis, C. (2001). Chronic heat-induced skin lesions (Erythema ab Igne): Ultrastructural studies. Ultrastructural Pathology, 25(2), 93-97.

Chronic heat-induced skin lesions (Erythema ab Igne) : Ultrastructural studies. / Cavallari, V.; Cicciarello, R.; Torre, V.; Ester Gagliardi, M.; Albiero, F.; Palazzo, R.; Siragusa, M.; Schipis, C.

In: Ultrastructural Pathology, Vol. 25, No. 2, 2001, p. 93-97.

Research output: Contribution to journalArticle

Cavallari, V, Cicciarello, R, Torre, V, Ester Gagliardi, M, Albiero, F, Palazzo, R, Siragusa, M & Schipis, C 2001, 'Chronic heat-induced skin lesions (Erythema ab Igne): Ultrastructural studies', Ultrastructural Pathology, vol. 25, no. 2, pp. 93-97.
Cavallari V, Cicciarello R, Torre V, Ester Gagliardi M, Albiero F, Palazzo R et al. Chronic heat-induced skin lesions (Erythema ab Igne): Ultrastructural studies. Ultrastructural Pathology. 2001;25(2):93-97.
Cavallari, V. ; Cicciarello, R. ; Torre, V. ; Ester Gagliardi, M. ; Albiero, F. ; Palazzo, R. ; Siragusa, M. ; Schipis, C. / Chronic heat-induced skin lesions (Erythema ab Igne) : Ultrastructural studies. In: Ultrastructural Pathology. 2001 ; Vol. 25, No. 2. pp. 93-97.
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