Chronic lymphocytic leukaemia: New biological and therapeutical insights

Giovanni D'Arena; Michael J. Keating; Mario Carotenuto

Chronic lymphocytic leukaemia: New biological and therapeutical insights

Giovanni D'Arena, Michael J. Keating, Mario Carotenuto

IRCCS Centro di Riferimento Oncologico della Basilicata (CROB)

Research output: Contribution to journal › Article › peer-review

Abstract

Some of the most recent advances on biology and management of B-cell chronic lymphocytic leukaemia (BCLL) are reviewed. This paper stems from the presentations at the "Chronic lymphoproliferative disorders" session of the International Meeting "Recent Advances in Hematology 2000", helded in San Giovanni Rotondo, Italy, April 6-8, 2000. In particular, this paper focus on the biological significance of IgV mutations and CD38 expression, the quantitative expression of some antigens and their relevance in the differential diagnosis of B-cell chronic lymphoproliferative disorders (CLDs). Finally, the therapeutical shift from philosophy of palliation to the approach oriented toward obtaining a complete remission is examined in detail.

Original language	English
Pages (from-to)	289-296
Number of pages	8
Journal	Trasfusione del Sangue
Volume	45
Issue number	6
Publication status	Published - 2000

Keywords

Chronic lymphocytic leukaemia
Diagnostic criteria
Therapy

ASJC Scopus subject areas

Hematology
Immunology and Allergy

Fingerprint Dive into the research topics of 'Chronic lymphocytic leukaemia: New biological and therapeutical insights'. Together they form a unique fingerprint.

Cite this

@article{7579b37ca97143b5a8cae5d2ac48f3aa,

title = "Chronic lymphocytic leukaemia: New biological and therapeutical insights",

abstract = "Some of the most recent advances on biology and management of B-cell chronic lymphocytic leukaemia (BCLL) are reviewed. This paper stems from the presentations at the {"}Chronic lymphoproliferative disorders{"} session of the International Meeting {"}Recent Advances in Hematology 2000{"}, helded in San Giovanni Rotondo, Italy, April 6-8, 2000. In particular, this paper focus on the biological significance of IgV mutations and CD38 expression, the quantitative expression of some antigens and their relevance in the differential diagnosis of B-cell chronic lymphoproliferative disorders (CLDs). Finally, the therapeutical shift from philosophy of palliation to the approach oriented toward obtaining a complete remission is examined in detail.",

keywords = "Chronic lymphocytic leukaemia, Diagnostic criteria, Therapy",

author = "Giovanni D'Arena and Keating, {Michael J.} and Mario Carotenuto",

year = "2000",

language = "English",

volume = "45",

pages = "289--296",

journal = "Trasfusione del Sangue",

issn = "0041-1787",

publisher = "SIMTI Servizi",

number = "6",

}

TY - JOUR

T1 - Chronic lymphocytic leukaemia

T2 - New biological and therapeutical insights

AU - D'Arena, Giovanni

AU - Keating, Michael J.

AU - Carotenuto, Mario

PY - 2000

Y1 - 2000

N2 - Some of the most recent advances on biology and management of B-cell chronic lymphocytic leukaemia (BCLL) are reviewed. This paper stems from the presentations at the "Chronic lymphoproliferative disorders" session of the International Meeting "Recent Advances in Hematology 2000", helded in San Giovanni Rotondo, Italy, April 6-8, 2000. In particular, this paper focus on the biological significance of IgV mutations and CD38 expression, the quantitative expression of some antigens and their relevance in the differential diagnosis of B-cell chronic lymphoproliferative disorders (CLDs). Finally, the therapeutical shift from philosophy of palliation to the approach oriented toward obtaining a complete remission is examined in detail.

AB - Some of the most recent advances on biology and management of B-cell chronic lymphocytic leukaemia (BCLL) are reviewed. This paper stems from the presentations at the "Chronic lymphoproliferative disorders" session of the International Meeting "Recent Advances in Hematology 2000", helded in San Giovanni Rotondo, Italy, April 6-8, 2000. In particular, this paper focus on the biological significance of IgV mutations and CD38 expression, the quantitative expression of some antigens and their relevance in the differential diagnosis of B-cell chronic lymphoproliferative disorders (CLDs). Finally, the therapeutical shift from philosophy of palliation to the approach oriented toward obtaining a complete remission is examined in detail.

KW - Chronic lymphocytic leukaemia

KW - Diagnostic criteria

KW - Therapy

UR - http://www.scopus.com/inward/record.url?scp=77950668252&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77950668252&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:77950668252

VL - 45

SP - 289

EP - 296

JO - Trasfusione del Sangue

JF - Trasfusione del Sangue

SN - 0041-1787

IS - 6

ER -