Chronic myelogenous leukemia following kidney transplantation in a pediatric patient

M. Mignozzi, S. Picca

Research output: Contribution to journalArticlepeer-review

Abstract

The incidence of cancer is increased following kidney transplantation. Chronic myelogenous leukemia (CML) has been previously reported in ten adult patients and only one pediatric patient post kidney transplantation. We report one male patient aged 18.8 years, on chronic dialysis from the age of 2 years, who was transplanted from a cadaver donor at the age of 8 years. He was treated with recombinant human growth hormone (rhGH) before transplantation and with azathioprine after kidney transplantation. Eight years after transplantation, CML was diagnosed and he was successfully treated with hydroxyurea and α-interferon. The follow-up is 28 months. The possible role of the combined action of rhGH and azathioprine in CML genesis is discussed.

Original languageEnglish
Pages (from-to)852-853
Number of pages2
JournalPediatric Nephrology
Volume16
Issue number11
DOIs
Publication statusPublished - 2001

Keywords

  • Azathioprine
  • Chronic myelogenous leukemia
  • Growth hormone
  • Pediatric kidney transplantation

ASJC Scopus subject areas

  • Nephrology
  • Pediatrics, Perinatology, and Child Health

Fingerprint

Dive into the research topics of 'Chronic myelogenous leukemia following kidney transplantation in a pediatric patient'. Together they form a unique fingerprint.

Cite this