TY - JOUR
T1 - Chronic myeloproliferative neoplasms in the elderly
AU - Maffioli, Margherita
AU - Orlandi, Ester
AU - Passamonti, Francesco
PY - 2018/1/1
Y1 - 2018/1/1
N2 - This review focuses on the management of elderly patients with chronic myeloid leukemia and chronic myeloproliferative neoplasms, including polycythemia vera, essential thrombocythemia and primary myelofibrosis. Median age in these neoplasms is within the 6th decades of age. All new therapies can be done at any age without absolute contraindication. However, the selection of the precise therapy for the single patient is mandatory. For these reasons, an accurate definition of diagnosis and prognostication is necessary. Precision in disease definition and prognostication is definitively helpful for personalizing therapeutic approach.
AB - This review focuses on the management of elderly patients with chronic myeloid leukemia and chronic myeloproliferative neoplasms, including polycythemia vera, essential thrombocythemia and primary myelofibrosis. Median age in these neoplasms is within the 6th decades of age. All new therapies can be done at any age without absolute contraindication. However, the selection of the precise therapy for the single patient is mandatory. For these reasons, an accurate definition of diagnosis and prognostication is necessary. Precision in disease definition and prognostication is definitively helpful for personalizing therapeutic approach.
KW - Chronic myeloid leukemia
KW - Myelofibrosis
KW - Polycythemia
KW - Thrombocythemia
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U2 - 10.1016/j.ejim.2018.05.005
DO - 10.1016/j.ejim.2018.05.005
M3 - Article
AN - SCOPUS:85047292310
JO - European Journal of Internal Medicine
JF - European Journal of Internal Medicine
SN - 0953-6205
ER -