Chronic pancreatitis and pancreatic cancer.

Patrick Maisonneuve, Albert B. Lowenfels

Research output: Contribution to journalArticlepeer-review

Abstract

Pancreatic cancer is the fourth leading cause of cancer deaths in the USA in both sexes. Early diagnosis is difficult and the overall mortality rate is high. Individuals at high risk for pancreatic cancer include smokers, and persons with all forms of chronic alcoholic, metabolic, tropical or hereditary pancreatitis. The duration of exposure to inflammation seems to be the major factor involved in the transition from benign to malignant condition. Smoking, which appears to further accelerate the carcinogenic transformation, remains the strongest risk factor amenable to preventive intervention.

Original languageEnglish
Pages (from-to)32-37
Number of pages6
JournalDigestive Diseases
Volume20
Issue number1
Publication statusPublished - 2002

ASJC Scopus subject areas

  • Gastroenterology

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