Abstract
Chronic renal failure is an important risk factor in acute coronary syndromes. Patients with chronic renal failure have a worse in-hospital and long-term outcome than patients with normal renal function. Although chronic renal failure is associated with other risk factors (diabetes, hypertension, high Killip class, peripheral vascular disease), multivariate analysis of several studies has consistently shown that chronic renal failure significantly and independently affects outcome in patients with acute coronary syndrome. Such patients are treated less aggressively than patients with normal renal function: beta-blockers, aspirin and statins are less frequently used in the intensive care unit. Few data are available on the immediate and long-term effects of an aggressive strategy based on early coronary angiography and subsequent revascularization in such patients. Moreover, only few patients with advanced renal disease have been enrolled in trials comparing treatment modalities in acute coronary syndrome. However, when great care is taken to avoid high contrast medium load, blood loss and periprocedural hypotension, which may result in deterioration of renal function, interventional techniques may prove to be successful in improving outcome.
| Original language | Italian |
|---|---|
| Journal | Giornale Italiano di Cardiologia |
| Volume | 7 |
| Issue number | 4 SUPPL1 |
| Publication status | Published - Apr 2006 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
L'insufficienza renale cronica nelle sindromi coronariche acute. / De Servi, Stefano; Guastoni, Carlo; Mariani, Matteo; Poli, Arnaldo; D'Urbano, Maurizio; Poletti, Fabrizio; Seveso, Giovanni.
In: Giornale Italiano di Cardiologia, Vol. 7, No. 4 SUPPL1, 04.2006.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - L'insufficienza renale cronica nelle sindromi coronariche acute
AU - De Servi, Stefano
AU - Guastoni, Carlo
AU - Mariani, Matteo
AU - Poli, Arnaldo
AU - D'Urbano, Maurizio
AU - Poletti, Fabrizio
AU - Seveso, Giovanni
PY - 2006/4
Y1 - 2006/4
N2 - Chronic renal failure is an important risk factor in acute coronary syndromes. Patients with chronic renal failure have a worse in-hospital and long-term outcome than patients with normal renal function. Although chronic renal failure is associated with other risk factors (diabetes, hypertension, high Killip class, peripheral vascular disease), multivariate analysis of several studies has consistently shown that chronic renal failure significantly and independently affects outcome in patients with acute coronary syndrome. Such patients are treated less aggressively than patients with normal renal function: beta-blockers, aspirin and statins are less frequently used in the intensive care unit. Few data are available on the immediate and long-term effects of an aggressive strategy based on early coronary angiography and subsequent revascularization in such patients. Moreover, only few patients with advanced renal disease have been enrolled in trials comparing treatment modalities in acute coronary syndrome. However, when great care is taken to avoid high contrast medium load, blood loss and periprocedural hypotension, which may result in deterioration of renal function, interventional techniques may prove to be successful in improving outcome.
AB - Chronic renal failure is an important risk factor in acute coronary syndromes. Patients with chronic renal failure have a worse in-hospital and long-term outcome than patients with normal renal function. Although chronic renal failure is associated with other risk factors (diabetes, hypertension, high Killip class, peripheral vascular disease), multivariate analysis of several studies has consistently shown that chronic renal failure significantly and independently affects outcome in patients with acute coronary syndrome. Such patients are treated less aggressively than patients with normal renal function: beta-blockers, aspirin and statins are less frequently used in the intensive care unit. Few data are available on the immediate and long-term effects of an aggressive strategy based on early coronary angiography and subsequent revascularization in such patients. Moreover, only few patients with advanced renal disease have been enrolled in trials comparing treatment modalities in acute coronary syndrome. However, when great care is taken to avoid high contrast medium load, blood loss and periprocedural hypotension, which may result in deterioration of renal function, interventional techniques may prove to be successful in improving outcome.
KW - Acute coronary syndromes
KW - Chronic renal failure
UR - http://www.scopus.com/inward/record.url?scp=33745109637&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33745109637&partnerID=8YFLogxK
M3 - Articolo
C2 - 16749289
AN - SCOPUS:33745109637
VL - 7
JO - Giornale Italiano di Cardiologia
JF - Giornale Italiano di Cardiologia
SN - 1827-6806
IS - 4 SUPPL1
ER -