Insufficienza renale cronica secondaria a reflusso vescico-ureterale: è possibile la prevenzione?

Translated title of the contribution: Chronic renal failure secondary to vesicoureteral reflux: is the prevention possible?

E. Zamorani, B. Andreetta, R. Dall'Amico, G. Montini, G. Passerini Glazel, G. Zacchello

Research output: Contribution to journalArticlepeer-review

Abstract

Vesicoureteral reflux (VUR) is the commonest cause of end-stage renal failure reported by the ITALKID (Italian Register of Chronic Renal Failure) (CRF) in children (0-15 years). Herein we report 131 children (53 M and 78 F) with a diagnosis of VUR made in our Centre between 1987 and 1994. Diagnosis was made in 69% of cases (85/131) during the 1st year of life and in 31% of cases (47/131) afterwards. VUR was demonstrated following a prenatal ultrasonography suspicion in 24/131 and after symptoms such as urinary tract infection (94/131) and poor growth (6/131). 75/131 of patients were treated conservatively (continuous chemoprophylaxis) while 56/131 underwent an antireflux surgery. CRF was found in 14% (19/131) of cases even though the diagnosis of VUR was performed in most of the cases (79%) during the 1st year of life. In conclusion prenatal ultrasonography has a low sensibility in the diagnosis of VUR. In addition, an early diagnosis made during the 1st year of life do not prevent CRF. The study was carried out in a Centre where patients with urological problems are referred from a large part of Northern East of Italy and this may explain the high prevalence of CRF and of children receiving a surgical treatment.

Translated title of the contributionChronic renal failure secondary to vesicoureteral reflux: is the prevention possible?
Original languageItalian
Pages (from-to)7-9
Number of pages3
JournalPediatria Medica e Chirurgica
Volume19
Issue number1
Publication statusPublished - Jan 1997

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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