Chronic respiratory symptoms and occult gastroesophageal reflux. A prospective clinical study and results of surgical therapy

T. R. DeMeester, L. Bonavina, C. Iascone, J. V. Courtney, D. B. Skinner

Research output: Contribution to journalArticlepeer-review

Abstract

Seventy-seven patients with a primary complaint of persistent cough, wheezing, and/or recurrent pneumonia were evaluated for the presence of occult gastroesophageal reflux disease. Fifty-four patients (70%) had increased esophageal acid exposure on 24-hour pH monitoring of the distal esophagus. In 28% of these patients the respiratory symptoms were thought to be due to aspiration because they occurred during or within 3 minutes after a reflux episode. In the other patients, the respiratory symptoms were either induced by or were unrelated to reflux episodes. The number of respiratory symptoms reported by the patients with increased esophageal acid exposure was directly related to the presence of a nonspecific esophageal motility abnormality (p

Original languageEnglish
Pages (from-to)337-345
Number of pages9
JournalAnnals of Surgery
Volume211
Issue number3
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Surgery

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