EFFETTI TOSSICI SULLE MUCOSE DELL'ESOFAGO, STOMACO E COLON E SUL PANCREAS DOPO SOMMINISTRAZIONE CRONICA DI AZATIOPRINA E CICLOFOSFAMIDE NEI RATTI

Translated title of the contribution: Chronic treatment with azathioprine and cyclophosphamide in rats: Structural effects on esophagus, stomach, large bowel and pancreas

C. Mansi, M. Dodero, V. Savarino, A. Picciotto, G. Ciravegna, R. Testa, G. Celle

Research output: Contribution to journalArticlepeer-review

Abstract

Rats were subjected to chronic treatment with azathioprine and cyclophosphamide, dose ratios 1:1, 3:1, and 1:3, and a study was made of the toxic effects on the mucosa of the esophagus, stomach and colon and on the pancreatic parenchyma. No morphological alterations were seen in animals treated with dose ratios 1:1 and 3:1, but those given the 1:3 dose ratio died at an early stage.

Translated title of the contributionChronic treatment with azathioprine and cyclophosphamide in rats: Structural effects on esophagus, stomach, large bowel and pancreas
Original languageItalian
Pages (from-to)235-241
Number of pages7
JournalPathologica
Volume71
Issue number1012
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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