EFFETTI TOSSICI SULLE MUCOSE DELL'ESOFAGO, STOMACO E COLON E SUL PANCREAS DOPO SOMMINISTRAZIONE CRONICA DI AZATIOPRINA E CICLOFOSFAMIDE NEI RATTI

C. Mansi; M. Dodero; V. Savarino; A. Picciotto; G. Ciravegna; R. Testa; G. Celle

EFFETTI TOSSICI SULLE MUCOSE DELL'ESOFAGO, STOMACO E COLON E SUL PANCREAS DOPO SOMMINISTRAZIONE CRONICA DI AZATIOPRINA E CICLOFOSFAMIDE NEI RATTI

Translated title of the contribution: Chronic treatment with azathioprine and cyclophosphamide in rats: Structural effects on esophagus, stomach, large bowel and pancreas

C. Mansi, M. Dodero, V. Savarino, A. Picciotto, G. Ciravegna, R. Testa, G. Celle

Research output: Contribution to journal › Article › peer-review

Abstract

Rats were subjected to chronic treatment with azathioprine and cyclophosphamide, dose ratios 1:1, 3:1, and 1:3, and a study was made of the toxic effects on the mucosa of the esophagus, stomach and colon and on the pancreatic parenchyma. No morphological alterations were seen in animals treated with dose ratios 1:1 and 3:1, but those given the 1:3 dose ratio died at an early stage.

Translated title of the contribution	Chronic treatment with azathioprine and cyclophosphamide in rats: Structural effects on esophagus, stomach, large bowel and pancreas
Original language	Italian
Pages (from-to)	235-241
Number of pages	7
Journal	Pathologica
Volume	71
Issue number	1012
Publication status	Published - 1979

ASJC Scopus subject areas

Pathology and Forensic Medicine

Cite this

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title = "EFFETTI TOSSICI SULLE MUCOSE DELL'ESOFAGO, STOMACO E COLON E SUL PANCREAS DOPO SOMMINISTRAZIONE CRONICA DI AZATIOPRINA E CICLOFOSFAMIDE NEI RATTI",

abstract = "Rats were subjected to chronic treatment with azathioprine and cyclophosphamide, dose ratios 1:1, 3:1, and 1:3, and a study was made of the toxic effects on the mucosa of the esophagus, stomach and colon and on the pancreatic parenchyma. No morphological alterations were seen in animals treated with dose ratios 1:1 and 3:1, but those given the 1:3 dose ratio died at an early stage.",

author = "C. Mansi and M. Dodero and V. Savarino and A. Picciotto and G. Ciravegna and R. Testa and G. Celle",

year = "1979",

language = "Italian",

volume = "71",

pages = "235--241",

journal = "Pathologica",

issn = "0031-2983",

publisher = "Pacini Editore s.r.l.",

number = "1012",

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T1 - EFFETTI TOSSICI SULLE MUCOSE DELL'ESOFAGO, STOMACO E COLON E SUL PANCREAS DOPO SOMMINISTRAZIONE CRONICA DI AZATIOPRINA E CICLOFOSFAMIDE NEI RATTI

AU - Mansi, C.

AU - Dodero, M.

AU - Savarino, V.

AU - Picciotto, A.

AU - Ciravegna, G.

AU - Testa, R.

AU - Celle, G.

PY - 1979

Y1 - 1979

N2 - Rats were subjected to chronic treatment with azathioprine and cyclophosphamide, dose ratios 1:1, 3:1, and 1:3, and a study was made of the toxic effects on the mucosa of the esophagus, stomach and colon and on the pancreatic parenchyma. No morphological alterations were seen in animals treated with dose ratios 1:1 and 3:1, but those given the 1:3 dose ratio died at an early stage.

AB - Rats were subjected to chronic treatment with azathioprine and cyclophosphamide, dose ratios 1:1, 3:1, and 1:3, and a study was made of the toxic effects on the mucosa of the esophagus, stomach and colon and on the pancreatic parenchyma. No morphological alterations were seen in animals treated with dose ratios 1:1 and 3:1, but those given the 1:3 dose ratio died at an early stage.

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M3 - Articolo

C2 - 471544

AN - SCOPUS:0018778396

VL - 71

SP - 235

EP - 241

JO - Pathologica

JF - Pathologica

SN - 0031-2983

IS - 1012

ER -

EFFETTI TOSSICI SULLE MUCOSE DELL'ESOFAGO, STOMACO E COLON E SUL PANCREAS DOPO SOMMINISTRAZIONE CRONICA DI AZATIOPRINA E CICLOFOSFAMIDE NEI RATTI

Abstract

ASJC Scopus subject areas

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