Índice cronotrópico-metabólico na doença de Chagas

Translated title of the contribution: Chronotropic-metabolic index in Chagas' disease

Ana Luiza Lunardi Rocha, Manoel Otávio Da Costa Rocha, Bruno Otávio Soares Teixeira, Federico Lombardi, Cláudia Drumond Guimarães Abreu, Roberto José Bittencourt, Márcio Vinícius Lins Barros, Antonio Luiz Pinho Ribeiro

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Chronotropic incompetence is a common feature in Chagas' disease patients. New methodologies are now available to evaluate the chronotropic response in different subsets. The chronotropic-metabolic index (CMI) is one of these new indexes and quantifies the relationship between the increment of heart rate and the maximal oxygen consumption (VO2 max) during exercise testing. In normal subjects there is linear response and the index is round 1.0. The aim of the study was to evaluate the chronotropic response in healthy controls and Chagas' disease patients with and without left ventricular dysfunction, using CMI. Twenty-four controls and 171 Chagas' disease patients underwent a clinical protocol and maximal exercise testing. Chagas' disease patients were divided into two groups: Ch1 = patients with ejection fraction (EF) > 39% and Ch2= EF2 max during exercise. Both groups of Chagas' disease patients showed a less steep curve in the chronotropic-metabolic index (Ch1: 0.91±0.10, Ch2: 0.89±0.08) than controls (1.0±0.12, p<0.001). Chagas' disease patients with and without le ventricular dysfunction chronotropic incompetence may exhibit reduced chronotropic response to exercise, expressed by a less steep chronotropic-metabolic index.

Original languagePortuguese
Pages (from-to)373-376
Number of pages4
JournalRevista da Sociedade Brasileira de Medicina Tropical
Volume38
Issue number5
Publication statusPublished - Sep 2005

Fingerprint

Chagas Disease
Exercise
Ventricular Dysfunction
Left Ventricular Dysfunction
Clinical Protocols
Oxygen Consumption
Heart Rate

Keywords

  • Autonomic nervous system
  • Chagas' disease
  • Chronotropism

ASJC Scopus subject areas

  • Infectious Diseases
  • Parasitology

Cite this

Lunardi Rocha, A. L., Da Costa Rocha, M. O., Soares Teixeira, B. O., Lombardi, F., Guimarães Abreu, C. D., Bittencourt, R. J., ... Pinho Ribeiro, A. L. (2005). Índice cronotrópico-metabólico na doença de Chagas. Revista da Sociedade Brasileira de Medicina Tropical, 38(5), 373-376.

Índice cronotrópico-metabólico na doença de Chagas. / Lunardi Rocha, Ana Luiza; Da Costa Rocha, Manoel Otávio; Soares Teixeira, Bruno Otávio; Lombardi, Federico; Guimarães Abreu, Cláudia Drumond; Bittencourt, Roberto José; Lins Barros, Márcio Vinícius; Pinho Ribeiro, Antonio Luiz.

In: Revista da Sociedade Brasileira de Medicina Tropical, Vol. 38, No. 5, 09.2005, p. 373-376.

Research output: Contribution to journalArticle

Lunardi Rocha, AL, Da Costa Rocha, MO, Soares Teixeira, BO, Lombardi, F, Guimarães Abreu, CD, Bittencourt, RJ, Lins Barros, MV & Pinho Ribeiro, AL 2005, 'Índice cronotrópico-metabólico na doença de Chagas', Revista da Sociedade Brasileira de Medicina Tropical, vol. 38, no. 5, pp. 373-376.
Lunardi Rocha AL, Da Costa Rocha MO, Soares Teixeira BO, Lombardi F, Guimarães Abreu CD, Bittencourt RJ et al. Índice cronotrópico-metabólico na doença de Chagas. Revista da Sociedade Brasileira de Medicina Tropical. 2005 Sep;38(5):373-376.
Lunardi Rocha, Ana Luiza ; Da Costa Rocha, Manoel Otávio ; Soares Teixeira, Bruno Otávio ; Lombardi, Federico ; Guimarães Abreu, Cláudia Drumond ; Bittencourt, Roberto José ; Lins Barros, Márcio Vinícius ; Pinho Ribeiro, Antonio Luiz. / Índice cronotrópico-metabólico na doença de Chagas. In: Revista da Sociedade Brasileira de Medicina Tropical. 2005 ; Vol. 38, No. 5. pp. 373-376.
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