Abstract
A 2-year-old boy presented with a stage IV neuroblastoma and, despite surgical reduction of the tumor mass followed by chemotherapy and radiotherapy, he developed bilateral chylous pleural effusions. These proved resistant to traditional methods of treatment but were resolved with minimal discomfort to the child by intrapleural injections of chlorambucil chemically bound to antibodies raised by immunizing his father with irradiated tumor cells.
| Original language | English |
|---|---|
| Pages (from-to) | 179-181 |
| Number of pages | 3 |
| Journal | Journal of Pediatric Surgery |
| Volume | 20 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1985 |
Keywords
- chylous effusion
- immuno-directed chemotherapy
- Neuroblastoma
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Surgery
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Cite this
Melino, G., Tabara, Z. B., & Hobbs, J. R. (1985). Chylous effusions due to neuroblastoma resolved by intrapleural chlorambucil coupled to father's antibodies. Journal of Pediatric Surgery, 20(2), 179-181. https://doi.org/10.1016/S0022-3468(85)80298-0