Cigarette smoking and risk of cerebral sinus thrombosis in oral contraceptive users: A case-control study

Alfonso Ciccone, A. Gatti, M. Melis, G. Cossu, G. Boncoraglio, M. R. Carriero, S. Iurlaro, E. Agostoni

Research output: Contribution to journalArticle

Abstract

Idiopathic cerebral sinus thrombosis (CST) can cause death and serious neurological disability. It is unknown whether smoking, a major risk factor for arterial stroke, is a risk factor also for CST. This work explored the association between smoking and CST in a hospitalbased, multicentric, case-control study. In order to avoid the confounding effect of the different risk factors for CST, we analysed the homogeneous subgroup of oral contraceptive users. We compared the prevalence of smoking in a group of 43 young women with CST (cases), whose oral contraceptive use was the only known risk factor, with a sample of 255 healthy contraceptive users of similar age (controls). The prevalence of smoking in cases and controls was similar (26% vs. 29%). The age and geographic area-adjusted odds ratio was 0.9; 95% confidence interval, 0.4-1.8; p=0.7. Smoking in oral contraceptive users does not appear to be associated with CST.

Original languageEnglish
Pages (from-to)319-323
Number of pages5
JournalNeurological Sciences
Volume26
Issue number5
DOIs
Publication statusPublished - Dec 2005

Fingerprint

Intracranial Sinus Thrombosis
Intracranial Thrombosis
Oral Contraceptives
Case-Control Studies
Smoking
Contraceptive Agents
Cause of Death
Stroke
Odds Ratio
Confidence Intervals

Keywords

  • Case-control studies
  • Cerebral venous thrombosis
  • Oral contraceptives
  • Risk factors
  • Smoking

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Cite this

Cigarette smoking and risk of cerebral sinus thrombosis in oral contraceptive users : A case-control study. / Ciccone, Alfonso; Gatti, A.; Melis, M.; Cossu, G.; Boncoraglio, G.; Carriero, M. R.; Iurlaro, S.; Agostoni, E.

In: Neurological Sciences, Vol. 26, No. 5, 12.2005, p. 319-323.

Research output: Contribution to journalArticle

Ciccone, Alfonso ; Gatti, A. ; Melis, M. ; Cossu, G. ; Boncoraglio, G. ; Carriero, M. R. ; Iurlaro, S. ; Agostoni, E. / Cigarette smoking and risk of cerebral sinus thrombosis in oral contraceptive users : A case-control study. In: Neurological Sciences. 2005 ; Vol. 26, No. 5. pp. 319-323.
@article{ac2608bf8a834d388503754b659a12e2,
title = "Cigarette smoking and risk of cerebral sinus thrombosis in oral contraceptive users: A case-control study",
abstract = "Idiopathic cerebral sinus thrombosis (CST) can cause death and serious neurological disability. It is unknown whether smoking, a major risk factor for arterial stroke, is a risk factor also for CST. This work explored the association between smoking and CST in a hospitalbased, multicentric, case-control study. In order to avoid the confounding effect of the different risk factors for CST, we analysed the homogeneous subgroup of oral contraceptive users. We compared the prevalence of smoking in a group of 43 young women with CST (cases), whose oral contraceptive use was the only known risk factor, with a sample of 255 healthy contraceptive users of similar age (controls). The prevalence of smoking in cases and controls was similar (26{\%} vs. 29{\%}). The age and geographic area-adjusted odds ratio was 0.9; 95{\%} confidence interval, 0.4-1.8; p=0.7. Smoking in oral contraceptive users does not appear to be associated with CST.",
keywords = "Case-control studies, Cerebral venous thrombosis, Oral contraceptives, Risk factors, Smoking",
author = "Alfonso Ciccone and A. Gatti and M. Melis and G. Cossu and G. Boncoraglio and Carriero, {M. R.} and S. Iurlaro and E. Agostoni",
year = "2005",
month = "12",
doi = "10.1007/s10072-005-0507-5",
language = "English",
volume = "26",
pages = "319--323",
journal = "Neurological Sciences",
issn = "1590-1874",
publisher = "Springer-Verlag Italia s.r.l.",
number = "5",

}

TY - JOUR

T1 - Cigarette smoking and risk of cerebral sinus thrombosis in oral contraceptive users

T2 - A case-control study

AU - Ciccone, Alfonso

AU - Gatti, A.

AU - Melis, M.

AU - Cossu, G.

AU - Boncoraglio, G.

AU - Carriero, M. R.

AU - Iurlaro, S.

AU - Agostoni, E.

PY - 2005/12

Y1 - 2005/12

N2 - Idiopathic cerebral sinus thrombosis (CST) can cause death and serious neurological disability. It is unknown whether smoking, a major risk factor for arterial stroke, is a risk factor also for CST. This work explored the association between smoking and CST in a hospitalbased, multicentric, case-control study. In order to avoid the confounding effect of the different risk factors for CST, we analysed the homogeneous subgroup of oral contraceptive users. We compared the prevalence of smoking in a group of 43 young women with CST (cases), whose oral contraceptive use was the only known risk factor, with a sample of 255 healthy contraceptive users of similar age (controls). The prevalence of smoking in cases and controls was similar (26% vs. 29%). The age and geographic area-adjusted odds ratio was 0.9; 95% confidence interval, 0.4-1.8; p=0.7. Smoking in oral contraceptive users does not appear to be associated with CST.

AB - Idiopathic cerebral sinus thrombosis (CST) can cause death and serious neurological disability. It is unknown whether smoking, a major risk factor for arterial stroke, is a risk factor also for CST. This work explored the association between smoking and CST in a hospitalbased, multicentric, case-control study. In order to avoid the confounding effect of the different risk factors for CST, we analysed the homogeneous subgroup of oral contraceptive users. We compared the prevalence of smoking in a group of 43 young women with CST (cases), whose oral contraceptive use was the only known risk factor, with a sample of 255 healthy contraceptive users of similar age (controls). The prevalence of smoking in cases and controls was similar (26% vs. 29%). The age and geographic area-adjusted odds ratio was 0.9; 95% confidence interval, 0.4-1.8; p=0.7. Smoking in oral contraceptive users does not appear to be associated with CST.

KW - Case-control studies

KW - Cerebral venous thrombosis

KW - Oral contraceptives

KW - Risk factors

KW - Smoking

UR - http://www.scopus.com/inward/record.url?scp=30744441169&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=30744441169&partnerID=8YFLogxK

U2 - 10.1007/s10072-005-0507-5

DO - 10.1007/s10072-005-0507-5

M3 - Article

C2 - 16388365

AN - SCOPUS:30744441169

VL - 26

SP - 319

EP - 323

JO - Neurological Sciences

JF - Neurological Sciences

SN - 1590-1874

IS - 5

ER -