Abstract
Introduction. Cigarette smoking is a major health hazard and may impair the normal sexual response. Aim. To evaluate (in the early follicular phase, and independently from sexual stimulation) in young, eumenorrheic, healthy, lean women the general and genital vascular effects of the smoking habit. Methods. One hundred thirty-seven patients undertook, in the early follicular phase of the menstrual cycle (day 3-5): the administration of the two-factor Italian McCoy Female Sexuality Questionnaire (MFSQ); two-dimensional (2-D) color Doppler evaluation of the ophthalmic, carotid, uterine, clitoral, and labia minora arteries; three-dimensional (3-D) analysis of clitoral and labia minora vascularization; and blood pressure evaluation. Fasting blood samples were drawn to test plasma estradiol, androstenedione, and testosterone circulating levels. Main Outcome Measures. The two-factor Italian MFSQ; the pulsatility index (PI) of internal carotid, ophthalmic, uterine, clitoral, and labia minora arteries; the vascularization index (VI), the flow index (FI), and the vascularization flow index (VFI) of clitoral body and labia minora, blood pressure measurement, and hormonal assay. Results. The subjects were divided in: nonsmokers (Group I; N=72); current (>2 years) light smokers-1 to 10 cigarettes/day-(Group II; N=35); and current heavy smokers->10 cigarettes/day-(Group III; N=30). The 2-D Doppler analysis of the ophthalmic and internal carotid arteries showed significant increased resistance in Group III compared with Group II and Group I. The genital vessels (uterine, clitoral, and labium minus arteries) showed the lowest PIs in the nonsmokers. The 3-D power Doppler histogram analysis of clitoral and labium minus blood flow showed the worst vascular indices (VI, FI, VFI) in the heavy smokers. Conclusions. Cigarette smoking may favor a reduced central and peripheral tissue perfusion with consequent increased risk of cerebrovascular and cardiovascular diseases and with genital vessels stiffness and impaired sexual performances.
| Original language | English |
|---|---|
| Pages (from-to) | 1717-1725 |
| Number of pages | 9 |
| Journal | Journal of Sexual Medicine |
| Volume | 8 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Jun 2011 |
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Keywords
- Clitoris
- Doppler
- Genital Blood Flow
- Labia Minora
- Smoking
- Ultrasound
ASJC Scopus subject areas
- Urology
- Obstetrics and Gynaecology
- Reproductive Medicine
Cite this
Cigarette Smoking Decreases the Genital Vascularization in Young Healthy, Eumenorrheic Women. / Battaglia, Cesare; Battaglia, Bruno; Mancini, Fulvia; Persico, Nicola; Nappi, Rossella E.; Paradisi, Roberto; Venturoli, Stefano.
In: Journal of Sexual Medicine, Vol. 8, No. 6, 06.2011, p. 1717-1725.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cigarette Smoking Decreases the Genital Vascularization in Young Healthy, Eumenorrheic Women
AU - Battaglia, Cesare
AU - Battaglia, Bruno
AU - Mancini, Fulvia
AU - Persico, Nicola
AU - Nappi, Rossella E.
AU - Paradisi, Roberto
AU - Venturoli, Stefano
PY - 2011/6
Y1 - 2011/6
N2 - Introduction. Cigarette smoking is a major health hazard and may impair the normal sexual response. Aim. To evaluate (in the early follicular phase, and independently from sexual stimulation) in young, eumenorrheic, healthy, lean women the general and genital vascular effects of the smoking habit. Methods. One hundred thirty-seven patients undertook, in the early follicular phase of the menstrual cycle (day 3-5): the administration of the two-factor Italian McCoy Female Sexuality Questionnaire (MFSQ); two-dimensional (2-D) color Doppler evaluation of the ophthalmic, carotid, uterine, clitoral, and labia minora arteries; three-dimensional (3-D) analysis of clitoral and labia minora vascularization; and blood pressure evaluation. Fasting blood samples were drawn to test plasma estradiol, androstenedione, and testosterone circulating levels. Main Outcome Measures. The two-factor Italian MFSQ; the pulsatility index (PI) of internal carotid, ophthalmic, uterine, clitoral, and labia minora arteries; the vascularization index (VI), the flow index (FI), and the vascularization flow index (VFI) of clitoral body and labia minora, blood pressure measurement, and hormonal assay. Results. The subjects were divided in: nonsmokers (Group I; N=72); current (>2 years) light smokers-1 to 10 cigarettes/day-(Group II; N=35); and current heavy smokers->10 cigarettes/day-(Group III; N=30). The 2-D Doppler analysis of the ophthalmic and internal carotid arteries showed significant increased resistance in Group III compared with Group II and Group I. The genital vessels (uterine, clitoral, and labium minus arteries) showed the lowest PIs in the nonsmokers. The 3-D power Doppler histogram analysis of clitoral and labium minus blood flow showed the worst vascular indices (VI, FI, VFI) in the heavy smokers. Conclusions. Cigarette smoking may favor a reduced central and peripheral tissue perfusion with consequent increased risk of cerebrovascular and cardiovascular diseases and with genital vessels stiffness and impaired sexual performances.
AB - Introduction. Cigarette smoking is a major health hazard and may impair the normal sexual response. Aim. To evaluate (in the early follicular phase, and independently from sexual stimulation) in young, eumenorrheic, healthy, lean women the general and genital vascular effects of the smoking habit. Methods. One hundred thirty-seven patients undertook, in the early follicular phase of the menstrual cycle (day 3-5): the administration of the two-factor Italian McCoy Female Sexuality Questionnaire (MFSQ); two-dimensional (2-D) color Doppler evaluation of the ophthalmic, carotid, uterine, clitoral, and labia minora arteries; three-dimensional (3-D) analysis of clitoral and labia minora vascularization; and blood pressure evaluation. Fasting blood samples were drawn to test plasma estradiol, androstenedione, and testosterone circulating levels. Main Outcome Measures. The two-factor Italian MFSQ; the pulsatility index (PI) of internal carotid, ophthalmic, uterine, clitoral, and labia minora arteries; the vascularization index (VI), the flow index (FI), and the vascularization flow index (VFI) of clitoral body and labia minora, blood pressure measurement, and hormonal assay. Results. The subjects were divided in: nonsmokers (Group I; N=72); current (>2 years) light smokers-1 to 10 cigarettes/day-(Group II; N=35); and current heavy smokers->10 cigarettes/day-(Group III; N=30). The 2-D Doppler analysis of the ophthalmic and internal carotid arteries showed significant increased resistance in Group III compared with Group II and Group I. The genital vessels (uterine, clitoral, and labium minus arteries) showed the lowest PIs in the nonsmokers. The 3-D power Doppler histogram analysis of clitoral and labium minus blood flow showed the worst vascular indices (VI, FI, VFI) in the heavy smokers. Conclusions. Cigarette smoking may favor a reduced central and peripheral tissue perfusion with consequent increased risk of cerebrovascular and cardiovascular diseases and with genital vessels stiffness and impaired sexual performances.
KW - Clitoris
KW - Doppler
KW - Genital Blood Flow
KW - Labia Minora
KW - Smoking
KW - Ultrasound
UR - http://www.scopus.com/inward/record.url?scp=79957919529&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79957919529&partnerID=8YFLogxK
U2 - 10.1111/j.1743-6109.2011.02257.x
DO - 10.1111/j.1743-6109.2011.02257.x
M3 - Article
C2 - 21477023
AN - SCOPUS:79957919529
VL - 8
SP - 1717
EP - 1725
JO - Journal of Sexual Medicine
JF - Journal of Sexual Medicine
SN - 1743-6095
IS - 6
ER -