Cigarette smoking in pregnancy and risk of pre-eclampsia

A. Spinillo, E. Capuzzo, T. O. Egbe, S. Nicola, G. Piazzi, F. Baltaro

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

The relationship between smoking in pregnancy and the development of pre-eclampsia has not been well studied. Smoking habits were prospectively evaluated in 117 patients with pre-eclampsia and 468 normotensive control pregnancies. Twenty cases (17.1%) and 120 controls (25.6%) reported smoking at any time during pregnancy. In stepwise multiple logistic regression analysis, smoking in pregnancy was a significant protective factor against the occurrence of pre-eclampsia (adjusted odds ratio = 0.50; 95% confidence interval 0.28-0.80, P = 0.018). On the other hand, a history of pre-eclampsia in previous pregnancies, low (<6th grade) educational level, a body mass index > 24 and maternal blood group AB were factors independently associated with an increased risk of pre-eclampsia. In conclusion, this study confirms that smoking in pregnancy reduces the risk of pre-eclampsia. However, the harmful consequences of smoking on pregnancy outcome far outweigh this risk reduction.

Original languageEnglish
Pages (from-to)771-775
Number of pages5
JournalJournal of Human Hypertension
Volume8
Issue number10
Publication statusPublished - 1994

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Pre-Eclampsia
Smoking
Pregnancy
Risk Reduction Behavior
Pregnancy Outcome
Blood Group Antigens
Habits
Logistic Models
Odds Ratio
Regression Analysis
Mothers
Confidence Intervals

Keywords

  • Pre-eclampsia
  • Risk factors
  • Smoking

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Spinillo, A., Capuzzo, E., Egbe, T. O., Nicola, S., Piazzi, G., & Baltaro, F. (1994). Cigarette smoking in pregnancy and risk of pre-eclampsia. Journal of Human Hypertension, 8(10), 771-775.

Cigarette smoking in pregnancy and risk of pre-eclampsia. / Spinillo, A.; Capuzzo, E.; Egbe, T. O.; Nicola, S.; Piazzi, G.; Baltaro, F.

In: Journal of Human Hypertension, Vol. 8, No. 10, 1994, p. 771-775.

Research output: Contribution to journalArticle

Spinillo, A, Capuzzo, E, Egbe, TO, Nicola, S, Piazzi, G & Baltaro, F 1994, 'Cigarette smoking in pregnancy and risk of pre-eclampsia', Journal of Human Hypertension, vol. 8, no. 10, pp. 771-775.
Spinillo A, Capuzzo E, Egbe TO, Nicola S, Piazzi G, Baltaro F. Cigarette smoking in pregnancy and risk of pre-eclampsia. Journal of Human Hypertension. 1994;8(10):771-775.
Spinillo, A. ; Capuzzo, E. ; Egbe, T. O. ; Nicola, S. ; Piazzi, G. ; Baltaro, F. / Cigarette smoking in pregnancy and risk of pre-eclampsia. In: Journal of Human Hypertension. 1994 ; Vol. 8, No. 10. pp. 771-775.
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