Abstract
The relationship between smoking in pregnancy and the development of pre-eclampsia has not been well studied. Smoking habits were prospectively evaluated in 117 patients with pre-eclampsia and 468 normotensive control pregnancies. Twenty cases (17.1%) and 120 controls (25.6%) reported smoking at any time during pregnancy. In stepwise multiple logistic regression analysis, smoking in pregnancy was a significant protective factor against the occurrence of pre-eclampsia (adjusted odds ratio = 0.50; 95% confidence interval 0.28-0.80, P = 0.018). On the other hand, a history of pre-eclampsia in previous pregnancies, low (<6th grade) educational level, a body mass index > 24 and maternal blood group AB were factors independently associated with an increased risk of pre-eclampsia. In conclusion, this study confirms that smoking in pregnancy reduces the risk of pre-eclampsia. However, the harmful consequences of smoking on pregnancy outcome far outweigh this risk reduction.
| Original language | English |
|---|---|
| Pages (from-to) | 771-775 |
| Number of pages | 5 |
| Journal | Journal of Human Hypertension |
| Volume | 8 |
| Issue number | 10 |
| Publication status | Published - 1994 |
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Keywords
- Pre-eclampsia
- Risk factors
- Smoking
ASJC Scopus subject areas
- Internal Medicine
Cite this
Cigarette smoking in pregnancy and risk of pre-eclampsia. / Spinillo, A.; Capuzzo, E.; Egbe, T. O.; Nicola, S.; Piazzi, G.; Baltaro, F.
In: Journal of Human Hypertension, Vol. 8, No. 10, 1994, p. 771-775.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cigarette smoking in pregnancy and risk of pre-eclampsia
AU - Spinillo, A.
AU - Capuzzo, E.
AU - Egbe, T. O.
AU - Nicola, S.
AU - Piazzi, G.
AU - Baltaro, F.
PY - 1994
Y1 - 1994
N2 - The relationship between smoking in pregnancy and the development of pre-eclampsia has not been well studied. Smoking habits were prospectively evaluated in 117 patients with pre-eclampsia and 468 normotensive control pregnancies. Twenty cases (17.1%) and 120 controls (25.6%) reported smoking at any time during pregnancy. In stepwise multiple logistic regression analysis, smoking in pregnancy was a significant protective factor against the occurrence of pre-eclampsia (adjusted odds ratio = 0.50; 95% confidence interval 0.28-0.80, P = 0.018). On the other hand, a history of pre-eclampsia in previous pregnancies, low (<6th grade) educational level, a body mass index > 24 and maternal blood group AB were factors independently associated with an increased risk of pre-eclampsia. In conclusion, this study confirms that smoking in pregnancy reduces the risk of pre-eclampsia. However, the harmful consequences of smoking on pregnancy outcome far outweigh this risk reduction.
AB - The relationship between smoking in pregnancy and the development of pre-eclampsia has not been well studied. Smoking habits were prospectively evaluated in 117 patients with pre-eclampsia and 468 normotensive control pregnancies. Twenty cases (17.1%) and 120 controls (25.6%) reported smoking at any time during pregnancy. In stepwise multiple logistic regression analysis, smoking in pregnancy was a significant protective factor against the occurrence of pre-eclampsia (adjusted odds ratio = 0.50; 95% confidence interval 0.28-0.80, P = 0.018). On the other hand, a history of pre-eclampsia in previous pregnancies, low (<6th grade) educational level, a body mass index > 24 and maternal blood group AB were factors independently associated with an increased risk of pre-eclampsia. In conclusion, this study confirms that smoking in pregnancy reduces the risk of pre-eclampsia. However, the harmful consequences of smoking on pregnancy outcome far outweigh this risk reduction.
KW - Pre-eclampsia
KW - Risk factors
KW - Smoking
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M3 - Article
VL - 8
SP - 771
EP - 775
JO - Journal of Human Hypertension
JF - Journal of Human Hypertension
SN - 0950-9240
IS - 10
ER -