Circadian clock gene Per3 variants influence the postpartum onset of bipolar disorder

S. Dallaspezia, C. Lorenzi, A. Pirovano, C. Colombo, E. Smeraldi, F. Benedetti

Research output: Contribution to journalArticlepeer-review

Abstract

Postpartum depression can mark the onset of bipolar disorder. The coding region of Per3 gene contains a variable-number tandem-repeat polymorphism, which has been shown to influence bipolar disorder onset and to affect breast cancer risk. We showed a relationship between Per3 polymorphism and postpartum depressive onset in bipolar disorder.

Original languageEnglish
Pages (from-to)138-140
Number of pages3
JournalEuropean Psychiatry
Volume26
Issue number3
DOIs
Publication statusPublished - Apr 2011

Keywords

  • Bipolar disorder
  • Clock genes
  • Per3 gene VNTR polymorphism
  • Postpartum depression

ASJC Scopus subject areas

  • Psychiatry and Mental health

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