Abstract
We used a chronobiological inferential statistical method to investigate circadian rhythms of hypophyseal hormones, cortisol, melatonin and catecholamines in two females of the same family affected by fatal familial insomnia. Case 1 (confirmed at autopsy) presented an absent or progressive loss of circadian rhythms of all hormones. In case 2 there was a loss of GH circadian rhythm and a less significant rhythm for melatonin, catecholamines and gonadotropins. These results confirm the role of the thalamus in regulating hormonal circadian rhythm.
| Original language | English |
|---|---|
| Pages (from-to) | 574-576 |
| Number of pages | 3 |
| Journal | Acta Neurologica |
| Volume | 13 |
| Issue number | 6 |
| Publication status | Published - Dec 1991 |
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ASJC Scopus subject areas
- Clinical Neurology
Cite this
Avoni, P., Cortelli, P., Montagna, P., Tinuper, P., Sforza, E., Contin, M., Parchi, P., Pierangeli, G., Maltoni, P., & Pavani, A. (1991). Circadian hormonal rhythms in two new cases of fatal familial insomnia. Acta Neurologica, 13(6), 574-576.