Abstract
We used a chronobiological inferential statistical method to investigate circadian rhythms of hypophyseal hormones, cortisol, melatonin and catecholamines in two females of the same family affected by fatal familial insomnia. Case 1 (confirmed at autopsy) presented an absent or progressive loss of circadian rhythms of all hormones. In case 2 there was a loss of GH circadian rhythm and a less significant rhythm for melatonin, catecholamines and gonadotropins. These results confirm the role of the thalamus in regulating hormonal circadian rhythm.
Original language | English |
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Pages (from-to) | 574-576 |
Number of pages | 3 |
Journal | Acta Neurologica |
Volume | 13 |
Issue number | 6 |
Publication status | Published - Dec 1991 |
ASJC Scopus subject areas
- Clinical Neurology