Circadian periodicity of plasma prolactin in some neurological diseases

E. Ferrari, A. Vailati, G. Nappi, E. Martignoni, P. A. Bossolo, A. Polleri

Research output: Contribution to journalArticlepeer-review


The circadian rhythmicity of plasma PRL has been studied in some neurological diseases in which hypothalamic involvement or abnormalities of brain neurotransmitters has been postulated. 11 Patients with Steinert's myotonic dystrophy, 7 with cluster headache and 10 with Huntington's chorea have been studied. By the mean cosinor procedure, a significant circadian rhythm of plasma PRL has been observed in Steinert's disease and in cluster headache, whereas a circadian periodicity is not detectable in Huntington's chorea, a degenerative disorder affecting the basal ganglia, the hypothalamus and many other areas of the CNS.

Original languageEnglish
Pages (from-to)231-242
Number of pages12
JournalInternational Journal of Chronobiology
Issue number4
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Medicine(all)


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