Circadian rhythmicity of prolactin secretion in elderly subjects: changes during bromocriptine treatment

Alessandro Polleri, P. Masturzo, G. Murialdo, A. Agnoli

Research output: Contribution to journalArticlepeer-review

Abstract

Prolactin has been taken as an index of neuroendocrine function in aging, where dopaminergic neurotransmission in considered to be impaired. The mean concentration of the hormone in the 24 h is higher in the aged men than in the adult controls. A sleep entrained periodicity is present in both aged subjects and controls, but a harmonic analysis of rhythmicity shows that secretory episodes have in aged men a slower periodicity than in adults. In aged men bromocriptine decreases the mean PRL values in the 24 h and the periodicity analysis shows the occurrence of harmonics with shorter period.

Original languageEnglish
Pages (from-to)317-321
Number of pages5
JournalJournal of Endocrinological Investigation
Volume4
Issue number3
DOIs
Publication statusPublished - 1981

Keywords

  • aging
  • bromocriptine
  • circadian rhythm
  • Prolactin

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

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