Circadian rhythmicity of prolactin secretion in Huntington's Chorea

A. Polleri, F. Savoldi, A. Muratorio, P. Masturzo, G. Murialdo, E. Martignoni, G. Nappi, A. Iudice, L. Murri

Research output: Contribution to journalArticlepeer-review


Prolactin circadian secretion has been studied in 16 males and in 8 females with Huntington's Chorea, in order to evaluate changes of the hormone's titres and of their periodicity in a condition where alterations of neurotransmission have been documented. Prolactin levels have been found normal, enhanced and low levels have been observed in one male case. Sleep connected surge has been found to be present in all cases. A harmonic analysis of periodical changes has been performed by a Fourier's cosines series. The changes in the occurence of different harmonic frequencies in respect to normal controls are not significant. No correlation could be drawn among clinical indices, hormone levels and the feature of the occurring harmonics.

Original languageEnglish
Pages (from-to)1609-1617
Number of pages9
JournalLife Sciences
Issue number19
Publication statusPublished - May 12 1980

ASJC Scopus subject areas

  • Pharmacology


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