Circadian Rhythms of Heart Rate Variability in Hypertrophic Cardiomyopathy

Stefano Guzzetti; Lubna Choudhury; Silvia Mezzetti; Chiara Cogliati; Paolo G. Camici; Alberto Malliani

Circadian Rhythms of Heart Rate Variability in Hypertrophic Cardiomyopathy

Stefano Guzzetti, Lubna Choudhury, Silvia Mezzetti, Chiara Cogliati, Paolo G. Camici, Alberto Malliani

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article

Abstract

Background: It has been hypothesized that an interaction between sympathetic nervous activity and an abnormal myocardium plays a role in the development and progression of hypertrophic cardiomyopathy (HCM). Methods: In the present study we investigated cardiac autonomic function by 24-hour spectral analysis of heart rate variability (HRV) in 18 patients with HCM, without evidence of heart failure, and 18 controls of similar age. Results: We found a significant reduction of 24 hour variance in HCM patients relative to controls (15,000 ± 9480 ms² vs 24,720 ± 12,450 ms² respectively; p

Original language	English
Pages (from-to)	349-353
Number of pages	5
Journal	Annals of Noninvasive Electrocardiology
Volume	1
Issue number	4
Publication status	Published - 1996

Keywords

Heart rate variability
Holter monitoring
Hypertrophic cardiomyopathy
Power spectral analysis
Sympathetic excitation

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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title = "Circadian Rhythms of Heart Rate Variability in Hypertrophic Cardiomyopathy",

abstract = "Background: It has been hypothesized that an interaction between sympathetic nervous activity and an abnormal myocardium plays a role in the development and progression of hypertrophic cardiomyopathy (HCM). Methods: In the present study we investigated cardiac autonomic function by 24-hour spectral analysis of heart rate variability (HRV) in 18 patients with HCM, without evidence of heart failure, and 18 controls of similar age. Results: We found a significant reduction of 24 hour variance in HCM patients relative to controls (15,000 ± 9480 ms2 vs 24,720 ± 12,450 ms2 respectively; p ",

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AU - Guzzetti, Stefano

AU - Choudhury, Lubna

AU - Mezzetti, Silvia

AU - Cogliati, Chiara

AU - Camici, Paolo G.

AU - Malliani, Alberto

PY - 1996

Y1 - 1996

N2 - Background: It has been hypothesized that an interaction between sympathetic nervous activity and an abnormal myocardium plays a role in the development and progression of hypertrophic cardiomyopathy (HCM). Methods: In the present study we investigated cardiac autonomic function by 24-hour spectral analysis of heart rate variability (HRV) in 18 patients with HCM, without evidence of heart failure, and 18 controls of similar age. Results: We found a significant reduction of 24 hour variance in HCM patients relative to controls (15,000 ± 9480 ms2 vs 24,720 ± 12,450 ms2 respectively; p

AB - Background: It has been hypothesized that an interaction between sympathetic nervous activity and an abnormal myocardium plays a role in the development and progression of hypertrophic cardiomyopathy (HCM). Methods: In the present study we investigated cardiac autonomic function by 24-hour spectral analysis of heart rate variability (HRV) in 18 patients with HCM, without evidence of heart failure, and 18 controls of similar age. Results: We found a significant reduction of 24 hour variance in HCM patients relative to controls (15,000 ± 9480 ms2 vs 24,720 ± 12,450 ms2 respectively; p

KW - Heart rate variability

KW - Holter monitoring

KW - Hypertrophic cardiomyopathy

KW - Power spectral analysis

KW - Sympathetic excitation

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