Circadian Rhythms of Heart Rate Variability in Hypertrophic Cardiomyopathy

Stefano Guzzetti, Lubna Choudhury, Silvia Mezzetti, Chiara Cogliati, Paolo G. Camici, Alberto Malliani

Research output: Contribution to journalArticlepeer-review


Background: It has been hypothesized that an interaction between sympathetic nervous activity and an abnormal myocardium plays a role in the development and progression of hypertrophic cardiomyopathy (HCM). Methods: In the present study we investigated cardiac autonomic function by 24-hour spectral analysis of heart rate variability (HRV) in 18 patients with HCM, without evidence of heart failure, and 18 controls of similar age. Results: We found a significant reduction of 24 hour variance in HCM patients relative to controls (15,000 ± 9480 ms2 vs 24,720 ± 12,450 ms2 respectively; p

Original languageEnglish
Pages (from-to)349-353
Number of pages5
JournalAnnals of Noninvasive Electrocardiology
Issue number4
Publication statusPublished - 1996


  • Heart rate variability
  • Holter monitoring
  • Hypertrophic cardiomyopathy
  • Power spectral analysis
  • Sympathetic excitation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Circadian Rhythms of Heart Rate Variability in Hypertrophic Cardiomyopathy'. Together they form a unique fingerprint.

Cite this