Abstract
Background: It has been hypothesized that an interaction between sympathetic nervous activity and an abnormal myocardium plays a role in the development and progression of hypertrophic cardiomyopathy (HCM). Methods: In the present study we investigated cardiac autonomic function by 24-hour spectral analysis of heart rate variability (HRV) in 18 patients with HCM, without evidence of heart failure, and 18 controls of similar age. Results: We found a significant reduction of 24 hour variance in HCM patients relative to controls (15,000 ± 9480 ms2 vs 24,720 ± 12,450 ms2 respectively; p
Original language | English |
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Pages (from-to) | 349-353 |
Number of pages | 5 |
Journal | Annals of Noninvasive Electrocardiology |
Volume | 1 |
Issue number | 4 |
Publication status | Published - 1996 |
Keywords
- Heart rate variability
- Holter monitoring
- Hypertrophic cardiomyopathy
- Power spectral analysis
- Sympathetic excitation
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine