Circadian variations of short-term heart period irreversibility in healthy and chronic heart failure patients

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We exploited time irreversibility analysis to characterize short heart period sequences (256 samples) derived from 24h Holter recordings in normal healthy (NO) subjects and chronic heart failure (CHF) patients. We found a significant presence of irreversible dynamics over short time scales, whereas over dominant, longer time scales irreversibility was marginal. Over short time scales in NO subjects the percentage of irreversible dynamics was larger during daytime than during nighttime, thus indicating a larger presence of non linear dynamics during daytime. Same circadian variation was detected in CHF patients but the percentage of irreversible series was higher. In NO subjects during daytime the non linear behavior was mostly the result of bradycardic runs shorter than tachycardie ones. In CHF population this pattern was as present as the reverse pattern (i.e. tachycardie runs shorter than bradycardic ones). Time irreversibility analysis provides useful and reliable indexes even in uncontrolled experimental conditions and during daily activities.

Original languageEnglish
Title of host publicationProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"
Pages2116-2119
Number of pages4
Publication statusPublished - 2008
Event30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada
Duration: Aug 20 2008Aug 25 2008

Other

Other30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
CountryCanada
CityVancouver, BC
Period8/20/088/25/08

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

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