Circannual rhythm of plasma thyrotropin in middle-aged and old euthyroid subjects

Manuela Simoni, A. Velardo, V. Montanini, M. Faustini Fustini, S. Seghedoni, P. Marrama

Research output: Contribution to journalArticle

Abstract

The circannual rhythm of plasma thyrotropin (TSH) was evaluated in 8,310 euthyroid, serially independent, young, middle-aged and old men and women. A statistically significant circannual rhythm of plasma TSH was validated, by the mean group-cosinor method, in the middle-aged and old men and women (p <0.05), with acrophase in December, whereas the young subjects did not show any rhythm. No significant correlation was found between TSH plasma levels and free thyroxine (fT4) or ambient temperature in any group. Moreover, plasma fT4 did not show seasonal variations.

Original languageEnglish
Pages (from-to)184-189
Number of pages6
JournalHormone Research in Paediatrics
Volume33
Issue number5
DOIs
Publication statusPublished - 1990

Fingerprint

Thyrotropin
Thyroxine
Temperature

Keywords

  • Ageing
  • Circannual rhythm
  • Free thyroxine
  • Thyrotropin

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Pediatrics, Perinatology, and Child Health

Cite this

Circannual rhythm of plasma thyrotropin in middle-aged and old euthyroid subjects. / Simoni, Manuela; Velardo, A.; Montanini, V.; Fustini, M. Faustini; Seghedoni, S.; Marrama, P.

In: Hormone Research in Paediatrics, Vol. 33, No. 5, 1990, p. 184-189.

Research output: Contribution to journalArticle

Simoni, Manuela ; Velardo, A. ; Montanini, V. ; Fustini, M. Faustini ; Seghedoni, S. ; Marrama, P. / Circannual rhythm of plasma thyrotropin in middle-aged and old euthyroid subjects. In: Hormone Research in Paediatrics. 1990 ; Vol. 33, No. 5. pp. 184-189.
@article{d3942b90ffa246dc8bec23b6923772c1,
title = "Circannual rhythm of plasma thyrotropin in middle-aged and old euthyroid subjects",
abstract = "The circannual rhythm of plasma thyrotropin (TSH) was evaluated in 8,310 euthyroid, serially independent, young, middle-aged and old men and women. A statistically significant circannual rhythm of plasma TSH was validated, by the mean group-cosinor method, in the middle-aged and old men and women (p <0.05), with acrophase in December, whereas the young subjects did not show any rhythm. No significant correlation was found between TSH plasma levels and free thyroxine (fT4) or ambient temperature in any group. Moreover, plasma fT4 did not show seasonal variations.",
keywords = "Ageing, Circannual rhythm, Free thyroxine, Thyrotropin",
author = "Manuela Simoni and A. Velardo and V. Montanini and Fustini, {M. Faustini} and S. Seghedoni and P. Marrama",
year = "1990",
doi = "10.1159/000181506",
language = "English",
volume = "33",
pages = "184--189",
journal = "Hormone Research in Paediatrics",
issn = "1663-2818",
publisher = "S. Karger AG",
number = "5",

}

TY - JOUR

T1 - Circannual rhythm of plasma thyrotropin in middle-aged and old euthyroid subjects

AU - Simoni, Manuela

AU - Velardo, A.

AU - Montanini, V.

AU - Fustini, M. Faustini

AU - Seghedoni, S.

AU - Marrama, P.

PY - 1990

Y1 - 1990

N2 - The circannual rhythm of plasma thyrotropin (TSH) was evaluated in 8,310 euthyroid, serially independent, young, middle-aged and old men and women. A statistically significant circannual rhythm of plasma TSH was validated, by the mean group-cosinor method, in the middle-aged and old men and women (p <0.05), with acrophase in December, whereas the young subjects did not show any rhythm. No significant correlation was found between TSH plasma levels and free thyroxine (fT4) or ambient temperature in any group. Moreover, plasma fT4 did not show seasonal variations.

AB - The circannual rhythm of plasma thyrotropin (TSH) was evaluated in 8,310 euthyroid, serially independent, young, middle-aged and old men and women. A statistically significant circannual rhythm of plasma TSH was validated, by the mean group-cosinor method, in the middle-aged and old men and women (p <0.05), with acrophase in December, whereas the young subjects did not show any rhythm. No significant correlation was found between TSH plasma levels and free thyroxine (fT4) or ambient temperature in any group. Moreover, plasma fT4 did not show seasonal variations.

KW - Ageing

KW - Circannual rhythm

KW - Free thyroxine

KW - Thyrotropin

UR - http://www.scopus.com/inward/record.url?scp=0025003404&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025003404&partnerID=8YFLogxK

U2 - 10.1159/000181506

DO - 10.1159/000181506

M3 - Article

C2 - 2272610

AN - SCOPUS:0025003404

VL - 33

SP - 184

EP - 189

JO - Hormone Research in Paediatrics

JF - Hormone Research in Paediatrics

SN - 1663-2818

IS - 5

ER -