Circulating and disseminated tumor cells in the clinical management of breast cancer patients: Unanswered questions

A. Amadori, E. Rossi, R. Zamarchi, P. Carli, D. Pastorelli, A. Jirillo

Research output: Contribution to journalArticle


Breast cancer is the most common cancer in women. Although survival rates have improved with the use of new therapeutic agents, many issues remain unresolved and new predictive and prognostic factors are needed in clinical practice. Several studies have suggested a prognostic and predictive role for circulating and disseminated tumor cells in metastatic disease and adjuvant treatment. Because of recent technological advances, oncologists have gained a new perspective on this disease. Circulating tumor cells could be both a new tumor marker as well as a tool to gain novel insight into the natural history of this neoplastic disease.

Original languageEnglish
Pages (from-to)375-386
Number of pages12
Issue number6
Publication statusPublished - May 2009



  • Breast cancer
  • Cell growth
  • Circulating tumor cells
  • Disseminated tumor cells
  • Prognostic factor

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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