Circulating biomarkers from tumour bulk to tumour machinery: Promises and pitfalls

M. Gion, M. G. Daidone

Research output: Contribution to journalArticlepeer-review


In this paper, we provide a working classification for circulating biomarkers according to their potential clinical application. We broadly divided biomarkers into four groups: (i) biomarkers of cancer risk, (ii) biomarkers of tumour-host interactions, (iii) biomarker of tumour burden, and (iv) function-related biomarkers. We hope this classification will provide a framework to which the results of future studies can be added. We also discuss the promises and pitfalls in the optional use of biomarkers in oncology.

Original languageEnglish
Pages (from-to)2613-2622
Number of pages10
JournalEuropean Journal of Cancer
Issue number17 SPEC. ISS.
Publication statusPublished - Nov 2004


  • Biomarkers
  • Cancer
  • Classification
  • Pitfalls

ASJC Scopus subject areas

  • Cancer Research
  • Hematology
  • Oncology


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