Circulating ghrelin concentrations in the polycystic ovary syndrome

Francesco Orio, Paola Lucidi, Stefano Palomba, Libuse Tauchmanova, Teresa Cascella, Tiziana Russo, Fulvio Zullo, Annamaria Colao, Gaetano Lombardi, Pierpaolo De Feo

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Abstract

Ghrelin is a novel gastric peptide which has orexigenic and adipogenic properties. Circulating ghrelin concentrations are influenced by nutritional status and, probably, regulate food intake and body weight. Obesity is a common feature in women with polycystic ovary syndrome (PCOS). To investigate the relationship of circulating ghrelin concentrations to the hormonal and metabolic features of PCOS women, plasma ghrelin and several hormone concentrations were evaluated in thirty-three women with PCOS and in thirty-two healthy women matched for age and body mass index (BM1). Plasma ghrelin concentrations were similar between the PCOS (179±27, pmol/1 ±SEM) and the control (181±24, pmol/1 ±SEM) groups. In both groups, there was a significant (p

Original languageEnglish
Pages (from-to)942-945
Number of pages4
JournalJournal of Clinical Endocrinology and Metabolism
Volume88
Issue number2
DOIs
Publication statusPublished - Feb 1 2003

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ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology, Diabetes and Metabolism

Cite this

Orio, F., Lucidi, P., Palomba, S., Tauchmanova, L., Cascella, T., Russo, T., Zullo, F., Colao, A., Lombardi, G., & De Feo, P. (2003). Circulating ghrelin concentrations in the polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 88(2), 942-945. https://doi.org/10.1210/jc.2002-021451