Abstract
The C1q-binding assay was performed on 30 sera from patients with Behcet's syndrome and circulating immune complexes were found in 46%. Circulating immune complexes were isolated and purified from the sera of two patients by immunoadsorption on a column of polymethylmetacrylate beads coated with C1q and then labelled with 125I. In double immunodiffusion these purified immune complexes were found to contain IgG, C1q, C1s and C3. Anti-IgG activity was not detectable in the purified immune complexes while specific cross-reactivity was found in a solid-phase radioimmunoassay with the majority of the sera of Behcet's syndrome.
| Original language | English |
|---|---|
| Pages (from-to) | 522-527 |
| Number of pages | 6 |
| Journal | Clinical and Experimental Immunology |
| Volume | 44 |
| Issue number | 3 |
| Publication status | Published - 1981 |
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ASJC Scopus subject areas
- Immunology
Cite this
Circulating immune complexes in Behcet's syndrome : Purification, characterization and cross-reactivity studies. / Valesini, G.; Picardo, M.; Pastore, R.; Pivetti, P.; Serafini, U.
In: Clinical and Experimental Immunology, Vol. 44, No. 3, 1981, p. 522-527.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Circulating immune complexes in Behcet's syndrome
T2 - Purification, characterization and cross-reactivity studies
AU - Valesini, G.
AU - Picardo, M.
AU - Pastore, R.
AU - Pivetti, P.
AU - Serafini, U.
PY - 1981
Y1 - 1981
N2 - The C1q-binding assay was performed on 30 sera from patients with Behcet's syndrome and circulating immune complexes were found in 46%. Circulating immune complexes were isolated and purified from the sera of two patients by immunoadsorption on a column of polymethylmetacrylate beads coated with C1q and then labelled with 125I. In double immunodiffusion these purified immune complexes were found to contain IgG, C1q, C1s and C3. Anti-IgG activity was not detectable in the purified immune complexes while specific cross-reactivity was found in a solid-phase radioimmunoassay with the majority of the sera of Behcet's syndrome.
AB - The C1q-binding assay was performed on 30 sera from patients with Behcet's syndrome and circulating immune complexes were found in 46%. Circulating immune complexes were isolated and purified from the sera of two patients by immunoadsorption on a column of polymethylmetacrylate beads coated with C1q and then labelled with 125I. In double immunodiffusion these purified immune complexes were found to contain IgG, C1q, C1s and C3. Anti-IgG activity was not detectable in the purified immune complexes while specific cross-reactivity was found in a solid-phase radioimmunoassay with the majority of the sera of Behcet's syndrome.
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UR - http://www.scopus.com/inward/citedby.url?scp=0019467899&partnerID=8YFLogxK
M3 - Article
C2 - 6976862
AN - SCOPUS:0019467899
VL - 44
SP - 522
EP - 527
JO - Clinical and Experimental Immunology
JF - Clinical and Experimental Immunology
SN - 0009-9104
IS - 3
ER -