Abstract
The study investigated possible menopause-related changes in circulating insulin-like growth factor binding protein 3 (IGFBP-3) levels and their relationship with insulin-like growth factor I (IGF-I) plasma levels. Forty-three healthy women, aged 45-55 years, were studied (22 premenopausal and 21 postmeno-pausal, matched for age and body mass index); in all subjects plasma IGF-I and IGFBP-3 levels were measured by radioimmunoassay. No difference was found between mean IGFBP-3 plasma levels in the two groups studied (premenopausal 3.42±0.49 v postmenopausal 3.46±0.58 mg/l), while mean IGF-I levels were significantly lower in postmenopausal as compared with premenopausal women (136.7±37.86 v 175.7±51.91 ng/ml, p
Original language | English |
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Pages (from-to) | 305-308 |
Number of pages | 4 |
Journal | Osteoporosis International |
Volume | 4 |
Issue number | 6 |
DOIs | |
Publication status | Published - Nov 1994 |
Keywords
- Insulin-like growth factor binding protein 3
- Menopause
ASJC Scopus subject areas
- Medicine(all)