Circulating levels of insulin-like growth factor binding protein 3 (IGFBP-3) and insulin-like growth factor I (IGF-I) in perimenopausal women

E. Romagnoli; S. Minisola; V. Carnevale; R. Rosso; M. T. Pacitti; A. Scarda; L. Scarnecchia; G. Mazzuoli

doi:10.1007/BF01622187

Circulating levels of insulin-like growth factor binding protein 3 (IGFBP-3) and insulin-like growth factor I (IGF-I) in perimenopausal women

E. Romagnoli, S. Minisola, V. Carnevale, R. Rosso, M. T. Pacitti, A. Scarda, L. Scarnecchia, G. Mazzuoli

IRCCS Casa Sollievo della Sofferenza

Research output: Contribution to journal › Article › peer-review

Abstract

The study investigated possible menopause-related changes in circulating insulin-like growth factor binding protein 3 (IGFBP-3) levels and their relationship with insulin-like growth factor I (IGF-I) plasma levels. Forty-three healthy women, aged 45-55 years, were studied (22 premenopausal and 21 postmeno-pausal, matched for age and body mass index); in all subjects plasma IGF-I and IGFBP-3 levels were measured by radioimmunoassay. No difference was found between mean IGFBP-3 plasma levels in the two groups studied (premenopausal 3.42±0.49 v postmenopausal 3.46±0.58 mg/l), while mean IGF-I levels were significantly lower in postmenopausal as compared with premenopausal women (136.7±37.86 v 175.7±51.91 ng/ml, p

Original language	English
Pages (from-to)	305-308
Number of pages	4
Journal	Osteoporosis International
Volume	4
Issue number	6
DOIs	https://doi.org/10.1007/BF01622187
Publication status	Published - Nov 1994

Keywords

Insulin-like growth factor binding protein 3
Menopause

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1007/BF01622187

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Circulating levels of insulin-like growth factor binding protein 3 (IGFBP-3) and insulin-like growth factor I (IGF-I) in perimenopausal women. / Romagnoli, E.; Minisola, S.; Carnevale, V.; Rosso, R.; Pacitti, M. T.; Scarda, A.; Scarnecchia, L.; Mazzuoli, G.

In: Osteoporosis International, Vol. 4, No. 6, 11.1994, p. 305-308.

Research output: Contribution to journal › Article › peer-review

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