Circulating prorenin and renin in response to intravenous adrenocorticotrophic hormone in essential hypertension

Chiara Troffa, Giancarlo Tonolo, Aldo Soro, Paolo Manunta, Maria G. Melis, Antonio Pazzola, Filippo Pala, Paolo Madeddu, Sergio Alagna, Antonello Masala, Nicola Glorioso

Research output: Contribution to journalArticle

Abstract

Plasma prorenin and renin changes after a bolus injection of 25 U intravenous adrenocorticotrophic hormone (ACTH, synacthen) were studied in seven untreated uncomplicated essential hypertensives over a period of 24 h. Plasma prorenin did not change significantly during the study, whereas renin after 24 h was higher than at baseline (4.3 ± 0.6 versus 2.3 ± 0.9 ng angiotensin I (Ang l)/ml per h, P

Original languageEnglish
Pages (from-to)S226-S227
JournalJournal of Hypertension, Supplement
Volume7
Publication statusPublished - 1989

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Keywords

  • Blood pressure
  • Glucocorticoids
  • Human renin gene expression

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine
  • Internal Medicine
  • Endocrinology

Cite this

Troffa, C., Tonolo, G., Soro, A., Manunta, P., Melis, M. G., Pazzola, A., Pala, F., Madeddu, P., Alagna, S., Masala, A., & Glorioso, N. (1989). Circulating prorenin and renin in response to intravenous adrenocorticotrophic hormone in essential hypertension. Journal of Hypertension, Supplement, 7, S226-S227.