Circulating tumor cells and mirnas as prognostic markers in neuroendocrine neoplasms

Maria Chiara Zatelli, Erika Maria Grossrubatscher, Elia Guadagno, Concetta Sciammarella, Antongiulio Faggiano, Annamaria Colao

Research output: Contribution to journalReview articlepeer-review


The prognosis of neuroendocrine neoplasms (NENs) is widely variable and has been shown to associate with several tissue- and blood-based biomarkers in different settings. The identification of prognostic factors predicting NEN outcome is of paramount importance to select the best clinical management for these patients. Prognostic markers have been intensively investigated, also taking advantage of the most modern techniques, in the perspective of personalized medicine and appropriate resource utilization. This review summarizes the available data on the possible role of circulating tumor cells and microRNAs as prognostic markers in NENs.

Original languageEnglish
Pages (from-to)R223-R237
JournalEndocrine-Related Cancer
Issue number6
Publication statusPublished - Jun 1 2017


  • Circulating biomarkers
  • CTC
  • Mirna
  • Neuroendocrine tumors
  • Prognosis

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Oncology
  • Endocrinology
  • Cancer Research


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