TY - JOUR
T1 - Circulating tumor cells and mirnas as prognostic markers in neuroendocrine neoplasms
AU - Zatelli, Maria Chiara
AU - Grossrubatscher, Erika Maria
AU - Guadagno, Elia
AU - Sciammarella, Concetta
AU - Faggiano, Antongiulio
AU - Colao, Annamaria
PY - 2017/6/1
Y1 - 2017/6/1
N2 - The prognosis of neuroendocrine neoplasms (NENs) is widely variable and has been shown to associate with several tissue- and blood-based biomarkers in different settings. The identification of prognostic factors predicting NEN outcome is of paramount importance to select the best clinical management for these patients. Prognostic markers have been intensively investigated, also taking advantage of the most modern techniques, in the perspective of personalized medicine and appropriate resource utilization. This review summarizes the available data on the possible role of circulating tumor cells and microRNAs as prognostic markers in NENs.
AB - The prognosis of neuroendocrine neoplasms (NENs) is widely variable and has been shown to associate with several tissue- and blood-based biomarkers in different settings. The identification of prognostic factors predicting NEN outcome is of paramount importance to select the best clinical management for these patients. Prognostic markers have been intensively investigated, also taking advantage of the most modern techniques, in the perspective of personalized medicine and appropriate resource utilization. This review summarizes the available data on the possible role of circulating tumor cells and microRNAs as prognostic markers in NENs.
KW - Circulating biomarkers
KW - CTC
KW - Mirna
KW - Neuroendocrine tumors
KW - Prognosis
UR - http://www.scopus.com/inward/record.url?scp=85019618764&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85019618764&partnerID=8YFLogxK
U2 - 10.1530/ERC-17-0091
DO - 10.1530/ERC-17-0091
M3 - Review article
AN - SCOPUS:85019618764
VL - 24
SP - R223-R237
JO - Endocrine-Related Cancer
JF - Endocrine-Related Cancer
SN - 1351-0088
IS - 6
ER -