Circulating tumor cells count predicts survival in colorectal cancer patients

Adriana Romiti, Salvatore Raffa, Roberta Di Rocco, Michela Roberto, Annalisa Milano, Angelo Zullo, Laura Leone, Danilo Ranieri, Francesca Mazzetta, Emanuela Medda, Ida Sarcina, Viola Barucca, Chiara D'Antonio, Valeria Durante, Mario Ferri, Maria Rosaria Torrisi, Paolo Marchetti

Research output: Contribution to journalArticlepeer-review

Abstract

Background & Aims: Data on the potential of circulating tumor cells (CTC) count in predicting overall survival (OS) in patients with colorectal cancer are timely and worthy of interest. This study aimed to evaluate the prognostic role of CTC count in both localized and metastatic colorectal cancer patients. Methods: Consecutive patients with histological diagnosis of colorectal cancer were enrolled. CTC count was performed, by using a quantitative immunofluorescence method, at baseline (T0) and 1 month following start of chemotherapy (T1). A CTC count

Original languageEnglish
Pages (from-to)279-284
Number of pages6
JournalJournal of Gastrointestinal and Liver Diseases
Volume23
Issue number3
DOIs
Publication statusPublished - 2014

Keywords

  • Circulating tumor cells
  • Colorectal cancer
  • Predictive value
  • Survival

ASJC Scopus subject areas

  • Gastroenterology

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