TY - JOUR
T1 - Circulating tumor cells in prostate cancer diagnosis and monitoring
T2 - An appraisal of clinical potential
AU - Galletti, Giuseppe
AU - Portella, Luigi
AU - Tagawa, Scott T.
AU - Kirby, Brian J.
AU - Giannakakou, Paraskevi
AU - Nanus, David M.
PY - 2014
Y1 - 2014
N2 - Circulating tumor cells (CTCs) have emerged as a viable solution to the lack of tumor tissue availability for patients with a variety of solid tumors, including prostate cancer. Different approaches have been used to capture this tumor cell population and several of these techniques have been used to assess the potential role of CTCs as a biological marker to predict treatment efficacy and clinical outcome. CTCs are now considered a strong tool to understand the molecular characteristics of prostate cancer, and to be used and analyzed as a 'liquid biopsy' in the attempt to grasp the biological portrait of the disease in the individual patient.
AB - Circulating tumor cells (CTCs) have emerged as a viable solution to the lack of tumor tissue availability for patients with a variety of solid tumors, including prostate cancer. Different approaches have been used to capture this tumor cell population and several of these techniques have been used to assess the potential role of CTCs as a biological marker to predict treatment efficacy and clinical outcome. CTCs are now considered a strong tool to understand the molecular characteristics of prostate cancer, and to be used and analyzed as a 'liquid biopsy' in the attempt to grasp the biological portrait of the disease in the individual patient.
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U2 - 10.1007/s40291-014-0101-8
DO - 10.1007/s40291-014-0101-8
M3 - Article
C2 - 24809501
AN - SCOPUS:84905683195
VL - 18
SP - 389
EP - 402
JO - Molecular Diagnosis and Therapy
JF - Molecular Diagnosis and Therapy
SN - 1177-1062
IS - 4
ER -