Circulation of two enterovirus C105 (EV-C105) lineages in Europe and Africa

A. Piralla, C. Daleno, A. Girello, S. Esposito, F. Baldanti

Research output: Contribution to journalArticlepeer-review


The coding sequences of five human enterovirus (HEV)-C genotype 105 strains recovered in Italy, Romania and Burundi from patients with upper and lower respiratory tract infections were analysed and phylogenetically compared with other circulating HEV-C strains. The EV-C105 was closely related to EV-C109 and EV-C118 strains. The European strains were similar to other circulating EV-C105 strains, while the two African EV-C105 clustered in separate bootstrapsupported (.0.90) branches of the P2 and P3 region trees. Minor inconsistencies in the clustering pattern of EV-C105 in the capsid region (P1) and non-capsid region (P3) suggest that recombination may have occurred in EV-C105 group B viruses. In conclusion, phylogenetic analysis revealed the circulation of two distinct EV-C105 lineages in Europe and Africa. A different pattern of evolution could be hypothesized for the two EV-C105 lineages.

Original languageEnglish
Pages (from-to)1374-1379
Number of pages6
JournalJournal of General Virology
Publication statusPublished - 2015

ASJC Scopus subject areas

  • Virology


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