Abstract
The dominance of the left atrium (LA) in the pulmonary vein (PV) regions for triggering and maintaining atrial fibrillation (AF) is now widely recognized. Radiofrequency (RF) PV isolation with electroanatomical guidance has recently emerged as a promising approach for AF treatment. We report the clinical outcome of the procedure in 251 consecutive patients with paroxysmal (n=179) or permanent (n=72) AF. Circular RF lesions were deployed transseptally during sinus rhythm or AF at 5 mm from PV ostia. Procedural and mapping times were 112±32 min and 75±27 min, respectively, with 29±11 min of fluoroscopy. Complete lesions (peak-to-peak bipolar electrogram amplitude 2, accounting for 28±9% of the total LA map surface. After 11±5 months, procedure success rates (freedom from AF without antiarrhythmic drugs) were 85% for paroxysmal and 68% for permanent AF. No PV stenoses were detected. By univariate analysis, an increased risk of recurrence was predicted by LA dilation (diameter >50 mm), AF duration, and a low ablated area (
| Original language | Italian |
|---|---|
| Journal | Recenti Progressi in Medicina |
| Volume | 92 |
| Issue number | 9 |
| Publication status | Published - Sep 2001 |
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ASJC Scopus subject areas
- Medicine(all)
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Prospettive nel trattamento della fibrillazione atriale. L'ablazione circonferenziale in radiofrequenza degli osti delle vene polmonari. / Pappone, Carlo; Rosanio, Salvatore; Oreto, Giuseppe; Tocchi, Monica; Gugliotta, Filippo; Salvati, Adriano; Dicandia, Cosimo; Mazzone, Patrizio; Santinelli, Vincenzo; Gulletta, Simone; Vicedomini, Gabriele.
In: Recenti Progressi in Medicina, Vol. 92, No. 9, 09.2001.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prospettive nel trattamento della fibrillazione atriale. L'ablazione circonferenziale in radiofrequenza degli osti delle vene polmonari
AU - Pappone, Carlo
AU - Rosanio, Salvatore
AU - Oreto, Giuseppe
AU - Tocchi, Monica
AU - Gugliotta, Filippo
AU - Salvati, Adriano
AU - Dicandia, Cosimo
AU - Mazzone, Patrizio
AU - Santinelli, Vincenzo
AU - Gulletta, Simone
AU - Vicedomini, Gabriele
PY - 2001/9
Y1 - 2001/9
N2 - The dominance of the left atrium (LA) in the pulmonary vein (PV) regions for triggering and maintaining atrial fibrillation (AF) is now widely recognized. Radiofrequency (RF) PV isolation with electroanatomical guidance has recently emerged as a promising approach for AF treatment. We report the clinical outcome of the procedure in 251 consecutive patients with paroxysmal (n=179) or permanent (n=72) AF. Circular RF lesions were deployed transseptally during sinus rhythm or AF at 5 mm from PV ostia. Procedural and mapping times were 112±32 min and 75±27 min, respectively, with 29±11 min of fluoroscopy. Complete lesions (peak-to-peak bipolar electrogram amplitude 2, accounting for 28±9% of the total LA map surface. After 11±5 months, procedure success rates (freedom from AF without antiarrhythmic drugs) were 85% for paroxysmal and 68% for permanent AF. No PV stenoses were detected. By univariate analysis, an increased risk of recurrence was predicted by LA dilation (diameter >50 mm), AF duration, and a low ablated area (
AB - The dominance of the left atrium (LA) in the pulmonary vein (PV) regions for triggering and maintaining atrial fibrillation (AF) is now widely recognized. Radiofrequency (RF) PV isolation with electroanatomical guidance has recently emerged as a promising approach for AF treatment. We report the clinical outcome of the procedure in 251 consecutive patients with paroxysmal (n=179) or permanent (n=72) AF. Circular RF lesions were deployed transseptally during sinus rhythm or AF at 5 mm from PV ostia. Procedural and mapping times were 112±32 min and 75±27 min, respectively, with 29±11 min of fluoroscopy. Complete lesions (peak-to-peak bipolar electrogram amplitude 2, accounting for 28±9% of the total LA map surface. After 11±5 months, procedure success rates (freedom from AF without antiarrhythmic drugs) were 85% for paroxysmal and 68% for permanent AF. No PV stenoses were detected. By univariate analysis, an increased risk of recurrence was predicted by LA dilation (diameter >50 mm), AF duration, and a low ablated area (
KW - Atrial fibrillation
KW - Electroanatomical mapping
KW - Pulmonary veins
KW - Radiofrequency ablation
UR - http://www.scopus.com/inward/record.url?scp=5844372184&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=5844372184&partnerID=8YFLogxK
M3 - Articolo
AN - SCOPUS:5844372184
VL - 92
JO - Recenti Progressi in Medicina
JF - Recenti Progressi in Medicina
SN - 0034-1193
IS - 9
ER -