In liver cirrhosis there is a progressive sodium retention by kidney, depending on a decreased renal perfusion by arteriolar vasoconscriction. Purpose of this study was to evaluate the usefulness of echo-color-Doppler, a non invasive procedure, in detecting haemodinamic impairment in cirrhotic patients. We studied 58 cirrhotic patients (28 females and 30 males), age ranged between 50 and 75 years; of these, 19 presented ascites, no patients had epato-renal syndrome, parenchymal of vascular renal disease, serum creatinine level was within normal value, no patients was treated by diuretics; 18 healthy subjects, not affected by liver and renal diseases, were studied as control group (11 males and 7 females), age ranged 47 and 74 years We measured Pulsatility Index (P.I.) and Resistivity Index (R.I.) by echo-Doppler at interlobular arterioles, visualized by color Doppler. Both parameters resulted to he higher in cirrhotics (P.I. = 1.46+/-0.25, R.I. = 0.76+/-0.08) that in control subjects (P.I. = 1.07+/-0.09, R.I. = 0.60+/-0.03). The difference was statistically significant, moreover both indexes resulted to be higher in cirrhotic patients with ascites than in those without. In conclusion our study confirmed other preliminary reports revealing that in liver cirrhosis there is an intrarenal vasoconscriction, already before ascites formation, this vasoconscriction can be well detected by echo color Doppler, a non invasive procedure, even in non advanced stages, viding informations for prognosis and therapy.
|Journal||Ultrasound in Medicine and Biology|
|Issue number||Suppl 1|
|Publication status||Published - 1997|
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging