Cis-Glyco-fused benzopyran compounds as new amyloid-β peptide ligands

Cristina Airoldi, Francisco Cardona, Erika Sironi, Laura Colombo, Mario Salmona, Artur Silva, Francesco Nicotra, Barbara La Ferla

Research output: Contribution to journalArticlepeer-review

Abstract

A small library of glyco-fused benzopyran compounds has been synthesised. Their interaction features with Aβ peptides have been characterised by using STD-NMR and trNOESY experiments. The conformational analysis of the compounds has also been carried out through molecular mechanics (MM) and molecular dynamics (MD) simulations.

Original languageEnglish
Pages (from-to)10266-10268
Number of pages3
JournalChemical Communications
Volume47
Issue number37
DOIs
Publication statusPublished - Oct 7 2011

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

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