Citicoline in patients with chronic cerebrovascular diseases (CCVD): Quantitative EEG study

A. Moglia, A. Arrigo, G. Bono

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

In the present double-blind study vs placebo, the effects of citicoline in patients with chronic cerebrovascular disease were evaluated with neurophysiological and neuropsychological procedures. The selected subjects (40 cases) received at random for periods of 4 weeks, intravenous infusion of citicoline 1000 mg/day or placebo, respectively. Within the citicoline group spectral EEG analysis revealed significant decrease of the slow delta frequencies paralleled by significant increase of the alpha activity. These results are discussed with reference to the positive changes observed also in neuropsychological performance tests recorded in patients with the same cerebrovascular disorders.

Original languageEnglish
Pages (from-to)309-313
Number of pages5
JournalCurrent Therapeutic Research
Volume36
Issue number2
Publication statusPublished - 1984

Fingerprint

Cytidine Diphosphate Choline
Cerebrovascular Disorders
Electroencephalography
Chronic Disease
Placebo Effect
Neuropsychological Tests
Double-Blind Method
Intravenous Infusions
Placebos

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Citicoline in patients with chronic cerebrovascular diseases (CCVD) : Quantitative EEG study. / Moglia, A.; Arrigo, A.; Bono, G.

In: Current Therapeutic Research, Vol. 36, No. 2, 1984, p. 309-313.

Research output: Contribution to journalArticle

Moglia, A. ; Arrigo, A. ; Bono, G. / Citicoline in patients with chronic cerebrovascular diseases (CCVD) : Quantitative EEG study. In: Current Therapeutic Research. 1984 ; Vol. 36, No. 2. pp. 309-313.
@article{1db1e3ea981d4e85b67d6a6922723d89,
title = "Citicoline in patients with chronic cerebrovascular diseases (CCVD): Quantitative EEG study",
abstract = "In the present double-blind study vs placebo, the effects of citicoline in patients with chronic cerebrovascular disease were evaluated with neurophysiological and neuropsychological procedures. The selected subjects (40 cases) received at random for periods of 4 weeks, intravenous infusion of citicoline 1000 mg/day or placebo, respectively. Within the citicoline group spectral EEG analysis revealed significant decrease of the slow delta frequencies paralleled by significant increase of the alpha activity. These results are discussed with reference to the positive changes observed also in neuropsychological performance tests recorded in patients with the same cerebrovascular disorders.",
author = "A. Moglia and A. Arrigo and G. Bono",
year = "1984",
language = "English",
volume = "36",
pages = "309--313",
journal = "Current Therapeutic Research - Clinical and Experimental",
issn = "0011-393X",
publisher = "Excerpta Medica",
number = "2",

}

TY - JOUR

T1 - Citicoline in patients with chronic cerebrovascular diseases (CCVD)

T2 - Quantitative EEG study

AU - Moglia, A.

AU - Arrigo, A.

AU - Bono, G.

PY - 1984

Y1 - 1984

N2 - In the present double-blind study vs placebo, the effects of citicoline in patients with chronic cerebrovascular disease were evaluated with neurophysiological and neuropsychological procedures. The selected subjects (40 cases) received at random for periods of 4 weeks, intravenous infusion of citicoline 1000 mg/day or placebo, respectively. Within the citicoline group spectral EEG analysis revealed significant decrease of the slow delta frequencies paralleled by significant increase of the alpha activity. These results are discussed with reference to the positive changes observed also in neuropsychological performance tests recorded in patients with the same cerebrovascular disorders.

AB - In the present double-blind study vs placebo, the effects of citicoline in patients with chronic cerebrovascular disease were evaluated with neurophysiological and neuropsychological procedures. The selected subjects (40 cases) received at random for periods of 4 weeks, intravenous infusion of citicoline 1000 mg/day or placebo, respectively. Within the citicoline group spectral EEG analysis revealed significant decrease of the slow delta frequencies paralleled by significant increase of the alpha activity. These results are discussed with reference to the positive changes observed also in neuropsychological performance tests recorded in patients with the same cerebrovascular disorders.

UR - http://www.scopus.com/inward/record.url?scp=0021232804&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021232804&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0021232804

VL - 36

SP - 309

EP - 313

JO - Current Therapeutic Research - Clinical and Experimental

JF - Current Therapeutic Research - Clinical and Experimental

SN - 0011-393X

IS - 2

ER -