In the present double-blind study vs placebo, the effects of citicoline in patients with chronic cerebrovascular disease were evaluated with neurophysiological and neuropsychological procedures. The selected subjects (40 cases) received at random for periods of 4 weeks, intravenous infusion of citicoline 1000 mg/day or placebo, respectively. Within the citicoline group spectral EEG analysis revealed significant decrease of the slow delta frequencies paralleled by significant increase of the alpha activity. These results are discussed with reference to the positive changes observed also in neuropsychological performance tests recorded in patients with the same cerebrovascular disorders.
|Number of pages||5|
|Journal||Current Therapeutic Research|
|Publication status||Published - 1984|
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