Citicoline in patients with chronic cerebrovascular diseases (CCVD): Quantitative EEG study

A. Moglia, A. Arrigo, G. Bono

Research output: Contribution to journalArticle

Abstract

In the present double-blind study vs placebo, the effects of citicoline in patients with chronic cerebrovascular disease were evaluated with neurophysiological and neuropsychological procedures. The selected subjects (40 cases) received at random for periods of 4 weeks, intravenous infusion of citicoline 1000 mg/day or placebo, respectively. Within the citicoline group spectral EEG analysis revealed significant decrease of the slow delta frequencies paralleled by significant increase of the alpha activity. These results are discussed with reference to the positive changes observed also in neuropsychological performance tests recorded in patients with the same cerebrovascular disorders.

Original languageEnglish
Pages (from-to)309-313
Number of pages5
JournalCurrent Therapeutic Research
Volume36
Issue number2
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Medicine(all)

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