CK-MB mass, troponin T, and troponin I after elective coronary stenting

Luigi La Vecchia, F. Bedogni, G. Mezzena, G. Finocchi, M. Martini, A. Castellani, M. Sartori, R. Ometto, G. Soffiati, M. Vincenzi

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To assess whether and to what extent elective coronary stenting (ECS) is associated with biochemical evidence of minor myocardial damage (MMD), as defined by the detection of abnormal post-procedural serum levels of CK-MB mass, Troponin T (Tn-T) and Troponin I (Tn-I). Methods: Nineteen elective procedures of single Palmaz-Schatz ECS were compared to a matched group of 25 conventional PTCA, performed between March and June, 1995. Acute myocardial infarction, total occlusions and dilatations of grafts were excluded. By definition, no patient (pt) had chest pain or ecg changes in the following 24 hours. After ECS, pts were treated with ticlopidine 400 mg/day. Baseline and post-procedural peak levels of each marker in the 2 groups were compared and related to clinical, angiographic and procedural variables. Upper limits of normality were: CK-MB=5ng/ml; Tn-T=0.2 ng/ml; Tn-I=0.6 ng/ml. Results: Baseline values were normal in all pts. In the stent group, CK-MB became positive in 2 pts, Tn-T in 4 and Tn-I in 7. Absolute changes in Tn-T and Tn-I were closely related to changes in CK-MB (r=0.76, p

Original languageEnglish
JournalChest
Volume110
Issue number4 SUPPL.
Publication statusPublished - Oct 1996

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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